Evidence map›Paper›PMID 40801071›Full record

ArticleSuicide & life-threatening behavior2025

Characteristics Differentiating Preadolescents With Suicidal Ideation From Those Who Display Suicidal Behaviors.

Laura Hennefield, Meghan Rose Donohue, Caroline P Hoyniak, Diana J Whalen, Renee J Thompson, Rebecca Tillman, Joan L Luby, Deanna M Barch

Abstract read
In one paragraph

Article in Suicide & life-threatening behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura HennefieldWashington University School of Medicine, Saint Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-5919-0342
Meghan Rose DonohueWashington University School of Medicine, Saint Louis, Missouri, USA.
Caroline P HoyniakWashington University School of Medicine, Saint Louis, Missouri, USA.
Diana J WhalenWashington University School of Medicine, Saint Louis, Missouri, USA.
Renee J ThompsonWashington University School of Medicine, Saint Louis, Missouri, USA.
Rebecca TillmanWashington University School of Medicine, Saint Louis, Missouri, USA.
Joan L LubyWashington University School of Medicine, Saint Louis, Missouri, USA.
Deanna M BarchWashington University School of Medicine, Saint Louis, Missouri, USA.

Funding

The Developmental Psychopathology of Suicidal Ideations and Cognitions in ChildhoodR01MH117436 · NIMH · WASHINGTON UNIVERSITY · PI BARCH, DEANNA, LUBY, JOAN L. · 2019 to 2023
$3.5M
Neurodevelopmental Emergence of Callous-Unemotional Behavior Beginning in Infancy: Neural Markers and Environmental Risk and Protective FactorsK23MH125023 · NIMH · WASHINGTON UNIVERSITY · PI DONOHUE, MEGHAN ROSE · 2021 to 2025
$904k
Suicidality in Young Children: Social and Cognitive Developmental Markers of Risk and ResiliencyK01MH127412 · NIMH · WASHINGTON UNIVERSITY · PI LAURA HENNEFIELD · 2022 to 2026
$897k
Influence of Physical Activity on Daily Positive Affect & Affective Neural Activity in PreschoolersK23MH118426 · NIMH · WASHINGTON UNIVERSITY · PI WHALEN, DIANA J · 2018 to 2022
$879k
NIMH NIH HHS K01 MH127412NIMH NIH HHS K23 MH118426NIMH NIH HHS K23 MH125023NIMH NIH HHS R01 MH117436
6 · The paper itself

Abstract

backgroundIncreases in suicide attempts in preadolescents represent a serious public health concern. This study aimed to identify prospective and concurrent risk factors that differentiate children with suicidal ideation (SI) from those with a suicide attempt (SA) across childhood.

method195 participants comprised of 8-12-year-olds from the Pediatric Suicidality Study, which followed a sample of preschoolers enriched for depression into preadolescence. Clinical diagnostic interviews and surveys to assess children's thoughts, behaviors, and experiences were administered to caregivers (preschool, preadolescence) and children (preadolescence).

resultsThree groups were created based on preadolescents' lifetime history of SI/SA: Suicide Attempt (SA; n = 25), Suicide Ideation without Attempt (SI-only; n = 102), and No SI/SA (n = 68). Compared to preadolescents with SI-only, preadolescents with SA exhibited increased depression (OR = 1.52), anxiety (OR = 1.32), maladaptive guilt (OR = 3.31), catastrophizing (OR = 1.24), stressful (OR = 1.20) and traumatic events (OR = 1.82) by preadolescence. Preadolescents with SA also exhibited increased anxiety (OR = 1.07) and maladaptive guilt during preschool (OR = 4.10). Family SA and social relationships did not differentiate groups.

conclusionsFindings demonstrate unique and separable risk factors for SI and SA in children under age 13 with clinical implications for assessing suicide risk. Alongside depression and anxiety, assessments of maladaptive guilt may be important to identify at-risk children for increased monitoring and intervention.

Indexed as

Suicidal IdeationSuicide, AttemptedAnxietyChildDepressionFemaleHumansMaleProspective StudiesRisk Factorschildpreadolescentsuicidal ideationsuicidesuicide attempt

Identifiers

PMID40801071
PMCPMC12607253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.