Evidence map›Paper›PMID 40801048›Full record

ArticleFood science & nutrition2025

Moderate Beer Consumption Ameliorated Aging-Related Metabolic Disorders Induced by D-Galactose in Mice via Modulating Gut Microbiota Dysbiosis.

Xueyuan Fu, Changwei Wang, Zhaoxia Yang, Junhong Yu, Jianfeng Wang, Wanxiu Cao, Chuyi Liu, Hua Yin, Bafang Li, Xiaomei Feng and 2 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xueyuan FuQingdao Marine Biomedical Research Institute Qingdao China.ORCID https://orcid.org/0009-0005-6973-3901
Changwei WangQingdao Marine Biomedical Research Institute Qingdao China.
Zhaoxia YangState Key Laboratory of Biological Fermentation Engineering of Beer Tsingtao Brewery Co., Ltd Qingdao China.
Junhong YuState Key Laboratory of Biological Fermentation Engineering of Beer Tsingtao Brewery Co., Ltd Qingdao China.
Jianfeng WangState Key Laboratory of Biological Fermentation Engineering of Beer Tsingtao Brewery Co., Ltd Qingdao China.
Wanxiu CaoQingdao Marine Biomedical Research Institute Qingdao China.
Chuyi LiuQingdao Marine Biomedical Research Institute Qingdao China.ORCID https://orcid.org/0000-0001-5092-9799
Hua YinState Key Laboratory of Biological Fermentation Engineering of Beer Tsingtao Brewery Co., Ltd Qingdao China.
Bafang LiQingdao Marine Biomedical Research Institute Qingdao China.
Xiaomei FengQingdao Marine Biomedical Research Institute Qingdao China.
Fen DuQingdao Marine Biomedical Research Institute Qingdao China.
Hu HouQingdao Marine Biomedical Research Institute Qingdao China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The process of aging is a multifaceted physiological phenomenon that entails the gradual deterioration of physical health. In recent years, fermented foods have garnered significant attention for their potential anti-aging benefits; however, the effects of moderate consumption of beer on aging-related metabolic disorders remain unexplored. Original beer, India Pale Ale (IPA), and Stout are widely consumed alcoholic beverages on a global scale. The objective of this study is to investigate and compare the effect of moderate consumption of these beers on aging-related metabolic disorders in mice induced by D-galactose (D-gal), encompassing inflammation, organ impairment, oxidative stress, and dyslipidemia. Furthermore, potential mechanisms were elucidated through analysis of gut microbiota. Compared to the Original beer, oral administration of IPA and Stout effectively improved liver and kidney health in mice. All beers mitigated serum oxidative damage induced by D-gal, with Stout exhibiting a more significant effect. Additionally, the Original beer was more effective at restoring intestinal microbiota diversity. Moreover, the tested beers elicited modifications in the composition of intestinal microbiota, including a decline in Firmicutes abundance and an elevation in Bacteroidota levels, accompanied by a decrease in harmful bacteria like Deferribacterota and an increase in beneficial bacteria like

Indexed as

aging‐related metabolic disordersd‐galactoseintestinal microbiotamoderate beer consumption

Identifiers

PMID40801048
PMCPMC12339418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.