Evidence map›Paper›PMID 40800991›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2025

Charting the path in rodent functional neuroimaging.

Alessandro Gozzi, Alexia Stuefer, Filomena Grazia Alvino, Valeria Bedin, Christopher Cover, Chaewon Kang, Alberto Galbusera, Rita Gil, Silvia Gini, Elizabeth de Guzman and 23 more

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biphasic acclimation for simultaneous wide-field fluorescent CaImaging neuroscience (Cambridge, Mass.) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Alessandro GozziFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.ORCID https://orcid.org/0000-0002-5731-4137
Alexia StueferFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Filomena Grazia AlvinoFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Valeria BedinFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Christopher CoverDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States.
Chaewon KangFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Alberto GalbuseraFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Rita GilChampalimaud Research, Champalimaud Foundation, Lisbon, Portugal.
Silvia GiniFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Elizabeth de GuzmanFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Gabriel Desrosiers-GrégoireComputational Brain Anatomy Laboratory, Cerebral Imaging Center, Douglas Mental Health University Institute, Montreal, Canada.
Daniel Gutierrez-BarraganFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Francesca MandinoDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, United States.
Jean-Charles MarianiFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Edoardo MicottiIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.
Henning ReimannBerlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrück Center for Molecular Medicine, Helmholtz Association of German Research Centers (HZ), Berlin, Germany.
Marco PaganiFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Chiara PepeFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
David Sastre-YagüeFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Mila UrosevicFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Mafalda ValenteChampalimaud Research, Champalimaud Foundation, Lisbon, Portugal.
Roberta VertulloFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Rossella CaneseIstituto Superiore di Sanità, Rome, Italy.
Anna DevorDepartment of Biomedical Engineering, Boston University, Boston, MA, United States.
Joanes GrandjeanDonders Institute for Brain, Behaviour, and Cognition, Radboud University, Nijmegen, The Netherlands.
Itamar KahnDepartment of Neuroscience and Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, United States.
Shella D KeiholzDepartment of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.
Evelyn M R LakeDepartment of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.
Nan LiAdvanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States.
Noam ShemeshChampalimaud Research, Champalimaud Foundation, Lisbon, Portugal.
Yen-Yu Ian ShihCenter for Animal MRI, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Valerio ZerbiDepartment of Psychiatry, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Nanyin ZhangDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, United States.

Funding

Project 4U19NS123717 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LINNINGER, ANDREAS A · 2021 to 2025
$13.4M
Circuit Mechanisms Governing the Default Mode NetworkR01MH126518 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Vinod Menon, Yen-Yu Ian Shih · 2021 to 2026
$4.3M
Mechanisms underlying positive and negative BOLD in the striatumRF1MH117053 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHIH, YEN-YU IAN · 2018 to 2019
$4.0M
Contribution of Ultra Low Frequency LFPs to Functional MRIR01NS078095 · NINDS · EMORY UNIVERSITY · PI KEILHOLZ, SHELLA D · 2012 to 2022
$3.4M
Chemogenetic Dissection of Neuronal and Astrocytic Compartment of the BOLD SignalR01MH111429 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHIH, YEN-YU IAN · 2016 to 2020
$2.7M
Multimodal imaging of prodromal synaptic, circuit, and network-level dysfunction in a murine model of Alzheimer's diseaseRF1NS130069 · NINDS · YALE UNIVERSITY · PI CAI, ZHENGXIN, LAKE, EVELYN MR · 2022 to 2022
$2.5M
SORDINO-fMRI for mouse brain applicationsR01EB033790 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Yen-Yu Ian Shih · 2023 to 2026
$2.5M
Impact of locus coeruleus-derived tau pathology in a rodent model of early Alzheimer's diseaseR01AG062581 · NIA · EMORY UNIVERSITY · PI KEILHOLZ, SHELLA D, WEINSHENKER, DAVID · 2020 to 2024
$2.3M
Functional dissection of therapeutic deep brain stimulation circuitryR01NS091236 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHIH, YEN-YU IAN · 2015 to 2019
$2.0M
9.4T Small Animal MRI scanner at UNCS10OD026796 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHIH, YEN-YU IAN · 2020 to 2020
$2.0M
Effects of intrinsic and drug-induced neuromodulation on functional brain imagingR01DA050159 · NIDA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI DEVOR, ANNA · 2020 to 2024
$1.9M
Metal-free, genetically encoded reporters for calcium recording with MRIR01NS128278 · NINDS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Tod Edward Kippin, Arnab Mukherjee · 2023 to 2026
$1.9M
NIA NIH HHS F30 AG079507NIA NIH HHS R01 AG062581NIA NIH HHS R21 AG075778NIA NIH HHS R21 AG083589NIBIB NIH HHS R01 EB029857NIBIB NIH HHS R01 EB033790NIDA NIH HHS R01 DA050159NIDA NIH HHS R21 DA057503NIH HHS S10 OD026796NIMH NIH HHS R01 MH111429NIMH NIH HHS R01 MH126518NIMH NIH HHS R41 MH113252NIMH NIH HHS RF1 MH117053NIMH NIH HHS S10 MH124745NINDS NIH HHS R01 NS078095NINDS NIH HHS R01 NS091236NINDS NIH HHS R01 NS128278NINDS NIH HHS R21 NS133913NINDS NIH HHS RF1 NS130069NINDS NIH HHS U19 NS123717
6 · The paper itself

Abstract

Driven by a period of accelerated progress and recent technical breakthroughs, whole-brain functional neuroimaging in rodents offers exciting new possibilities for addressing basic questions about brain function and its alterations. In response to lessons learned from the human neuroimaging community, leading scientists and researchers in the field convened to address existing barriers and outline ambitious goals for the future. This article captures these discussions, highlighting a shared vision to advance rodent functional neuroimaging into an era of increased impact.

Indexed as

anesthesiaawakefMRIfUSImouserat

Identifiers

PMID40800991
PMCPMC12319733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.