ArticleImaging neuroscience (Cambridge, Mass.)2025
Brain wiring economics, network organisation and population-level genomics.
Article in Imaging neuroscience (Cambridge, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Heterochronicity shapes brain network formation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- A decade of discovery: Leveraging genomic data in the ABCD study to illuminate adolescent neurodevelopment.Developmental cognitive neuroscience · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
What role do our genes play in shaping the structural organisation of the living human brain? Across a sample of 2,153 children (9-11 years old), we address this question, focusing on common genetic variants associated with cognitive ability and diffusion-based structural neuroimaging. Using polygenic scores, we test how variability in the genetic signal associated with cognitive ability is linked to simulated structural network properties, such as network efficiency. We fit a computational model to each connectome that simulates the emergence of high-level network properties. Central to the model is an economic trade-off between the "cost" of forming a given connection (a distance penalty) and the topological "value" that connection brings to the network. To simulate the network properties of those with the highest genetic propensity for cognitive ability, we had to use a significantly weaker
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.