Evidence map›Paper›PMID 40800710›Full record

ArticleIndian journal of anaesthesia2025

Lignocaine instilled through the suction channel of a subglottic suction drainage tracheal tube improves tube tolerance during extubation compared to intravenous lignocaine: A double-blinded randomised controlled trial.

R Sripriya, Jyotsna Namburu, Ghansham Biyani, Nageswara Rao Tangirala, Vaishakh Tharavath, Raza S Gouri

Abstract read
In one paragraph

Article in Indian journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

R SripriyaDepartment of Anaesthesiology, AIIMS Mangalagiri, Andhra Pradesh, India.ORCID https://orcid.org/0000-0003-1164-3610
Jyotsna NamburuDepartment of Anaesthesiology, AIIMS Mangalagiri, Andhra Pradesh, India.ORCID https://orcid.org/0009-0003-8890-1793
Ghansham BiyaniDepartment of Anaesthesiology, AIIMS Mangalagiri, Andhra Pradesh, India.ORCID https://orcid.org/0000-0002-7854-7001
Nageswara Rao TangiralaDepartment of Anaesthesiology, AIIMS Mangalagiri, Andhra Pradesh, India.ORCID https://orcid.org/0000-0002-1199-1124
Vaishakh TharavathDepartment of Anaesthesiology, AIIMS Mangalagiri, Andhra Pradesh, India.ORCID https://orcid.org/0000-0003-0373-4547
Raza S GouriDepartment of Anaesthesiology, AIIMS Mangalagiri, Andhra Pradesh, India.ORCID https://orcid.org/0000-0002-3178-1095

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Cough is frequently encountered during extubation. We propose a novel technique of utilising the suction port of a subglottic suction drainage endotracheal tube (SSD-ETT) to instil lignocaine around the cuff and improve tube tolerance during extubation. The primary objective was to assess the cough score during emergence. Secondary objectives included changes in haemodynamics and postoperative oropharyngeal morbidities. Methods: In total, 108 patients undergoing nasal surgery were tracheally intubated with the SSD-ETT and randomised to receive normal saline (NS) both intravenous and subglottic (Group C), subglottic NS and intravenous lignocaine (Group IVL), and subglottic lignocaine and intravenous NS (Group SGL) before reversal of residual neuromuscular blockade. The volume for subglottic administration was fixed at 3 mL of either 2% lignocaine or NS. The volume for intravenous administration was 1.5 mg/kg of 2% lignocaine or an equivalent volume of NS. Tube tolerance was graded using a 5-point qualitative cough score. Haemodynamics were recorded at baseline, post-intubation, and post-extubation. Postoperative oropharyngeal morbidities were also compared. Results: Seventy-five percent of patients in Group SGL had no cough, compared to 27.8% in Group IVL and 30% in Group C ( Conclusion: Subglottic instillation of lignocaine significantly improves tube tolerance during extubation and has favourable effects on heart rate compared to intravenous administration.

Indexed as

Anaesthesiacoughendotracheal tubeextubation responselignocainepostoperative sore throatsubglottic suction drainagetracheal extubation

Identifiers

PMID40800710
PMCPMC12338475

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.