ArticleJBMR plus2025
The mineralization of osteonal cement line depends on where the osteon is formed.
Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Strategic Placement of Pores to Modulate Toughness in Hydroxyapatite Bone Scaffolds Fixation.Biomimetics (Basel, Switzerland) · 2026Article
- Nano-scale evidence for osteocyte network integration across bone remodeling interfaces in human bone revealed by synchrotron nanoCT.Materials today. Bio · 2026Article
- Interdisciplinarity of secondary osteons: relevance of bioarchaeological and palaeontological research in biomedical cortical bone histology studies.Bone reports · 2026Review
- Phase-field simulation of crack growth in cortical bone microstructure: parameter identification and comparison against experiments.Biomechanics and modeling in mechanobiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cement line (CL) is a thin layer, 1-3 μm in width, separating secondary osteons from interstitial bone and other osteons. Despite the possible role for bone quality, the CL is still one of the least understood features of bone. This study aims to investigate how the mineral content of the CL varies not only with osteon age but also with the surrounding environment. Using quantitative backscattered electron imaging to measure the mineral content, we analyzed 35 osteons from femoral bone of 2 male individuals (40 and 81 yr old). We implemented a new approach to investigate the mineral content based on a spatially resolved analysis in layers along the CL and incorporating regions both inside the osteon (formed soon after CL deposition) and outside (already present at the time of CL deposition). We found that the CLs had always higher mineral content than the corresponding osteon (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.