Evidence map›Paper›PMID 40800664›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2025

Actigraphic assessment of delayed sleep-wake rhythm could predict functional impairment in patients with bipolar disorder.

Kazuhiro Kurihara, Futenma Kunihiro, Yoshikazu Takaesu

Abstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kazuhiro KuriharaDepartment of Neuropsychiatry Graduate School of Medicine University of the Ryukyus Ginowan Okinawa Japan.ORCID https://orcid.org/0000-0002-2032-3873
Futenma KunihiroDepartment of Neuropsychiatry Graduate School of Medicine University of the Ryukyus Ginowan Okinawa Japan.
Yoshikazu TakaesuDepartment of Neuropsychiatry Graduate School of Medicine University of the Ryukyus Ginowan Okinawa Japan.ORCID https://orcid.org/0000-0002-9169-3249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: A delayed sleep-wake rhythm is a common but often under-recognized characteristic of bipolar disorder (BD). This study aimed to examine the association between delayed sleep-wake rhythm and functional impairment using actigraphy. Methods: Participants with BD in clinical remission ( Results: Correlation analysis revealed a significant positive relationship between the midpoint of sleep and total WHODAS 2.0 scores ( Conclusion: Delayed sleep-wake rhythms may contribute to functional impairment in euthymic individuals with BD. These findings suggest that advancing sleep-wake rhythm may contribute to improvements in social functioning. Actigraphy holds potential as a digital biomarker for assessing functional outcomes in this population.

Indexed as

actigraphybipolar disordercircadian rhythmdelayed sleep–wake rhythmfunctional impairment

Identifiers

PMID40800664
PMCPMC12339665

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.