ArticleArthroplasty today2025
Outcomes of Long-Term Antibiotic Therapy for Prosthetic Joint Infection: A Cohort Study in a Canadian High-Volume Arthroplasty Center.
Article in Arthroplasty today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Long-term antibiotic therapy (LAT) can be used to prevent relapse of prosthetic joint infection. Evidence on best practices for LAT is limited and conflicting. We aimed to assess total hip or knee arthroplasty revision for prosthetic joint infection for patients on LAT. Methods: We identified a single-institution study cohort of patients who used oral antibiotics for longer than 90 days. We then performed a chart review to identify demographic and clinical characteristics of these patients at the index revision and the day LAT ended. We used Cox proportional hazard models to estimate the hazard ratios (HRs) of the association between these characteristics and later revision. Results: Our study cohort consisted of 85 patients (87 joints), 60% were male; median age was 65 years, and median body mass index was 32 kg/m Conclusions: Elevated C-reactive protein levels seem to be consistently associated with an increased risk of re-revision. We could not assess whether there is a threshold above which patients are at increased risk. Other factors, for example, increased age, may play a role, but we were unable to rule definitively on these factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.