ArticleImaging neuroscience (Cambridge, Mass.)2024
Characterisation of laminar and vascular spatiotemporal dynamics of CBV and BOLD signals using VASO and ME-GRE at 7T in humans.
Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Short-term gradient imperfections in high-resolution EPI lead to Fuzzy Ripple artifacts.Magnetic resonance in medicine · 2025Article
- In the brain of the beholder: bi-stable motion reveals mesoscopic-scale feedback modulation in V1.Brain structure & function · 2025Article
- Mapping curvature domains in human V4 using CBV-sensitive layer-fMRI at 3T.Frontiers in neuroscience · 2025Article
- Fuzzy ripple artifact in high resolution fMRI: identification, cause, and mitigation.bioRxiv : the preprint server for biology · 2024Article
- Multimodal laminar characterization of visual areas along the cortical hierarchy.Imaging neuroscience (Cambridge, Mass.)Article
- Laminar CBV and BOLD response characteristics over time and space in the human primary somatosensory cortex at 7T.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
- Update of
Authors and funding
8 authors.
Funding
Abstract
Interpretation of cortical laminar functional magnetic resonance imaging (fMRI) activity requires detailed knowledge of the spatiotemporal haemodynamic response across vascular compartments due to the well-known vascular biases (e.g., the draining veins). Further complications arise from the fact that the spatiotemporal haemodynamic response differs depending on the duration of stimulation. Information about haemodynamic response characteristics across different stimulus durations, cortical depth, and vascular compartments is crucial for future studies using depth-dependent cerebral blood volume (CBV) measurements, which promise higher specificity for the cortical microvasculature than the blood oxygenation level dependent (BOLD) contrast. To date, direct information about CBV dynamics with respect to stimulus duration, cortical depth, and vasculature is missing in humans. Therefore, we characterised the cortical depth-dependent CBV-haemodynamic responses across a wide set of stimulus durations with 0.9 mm isotropic spatial and 0.785 seconds effective temporal resolution in humans using slice-selective slab-inversion vascular space occupancy (SS-SI VASO). Additionally, we investigated signal contributions from macrovascular compartments using fine-scale vascular information from multi-echo gradient-echo (ME-GRE) data at 0.35 mm isotropic resolution. In total, this resulted in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.