ArticleImaging neuroscience (Cambridge, Mass.)2024
Quantifying human gray matter microstructure using neurite exchange imaging (NEXI) and 300 mT/m gradients.
Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Comparative Systematic Analysis of Gray Matter Biophysical Models on a Public Dataset.Magnetic resonance in medicine · 2026Article
- Dependence of the Extra-Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter.Magnetic resonance in medicine · 2026Article
- Steady-state water exchange in neural tissue is primarily passive and through the phospholipid bilayer.bioRxiv : the preprint server for biology · 2026Article
- Complementary Sensitivity of Fixed-Time and Fixed-Oscillation Regimes to Exchange and Structural Disorder in the Human Brain Revealed Using Oscillating-Gradient Diffusion MRI With Ultra-Strong Gradients.Magnetic resonance in medicine · 2026Article
- Diffusion MRI experimental design optimization for microstructure imaging.Communications biology · 2026Article
- Passive water exchange between multiple sites can explain why apparent exchange rate constants depend on ionic and osmotic conditions in gray matter.Magnetic resonance letters · 2026Article
- Visualizing cortical laminar architecture in the living human brain using next-generation ultra-high-gradient diffusion MRI.Communications biology · 2026Article
- Thermal noise lowers the accuracy of rotationally invariant harmonics of diffusion MRI data and their robustness to experimental variations.Magnetic resonance in medicine · 2026Article
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- Passive water exchange between multiple sites can explain why apparent exchange rate constants depend on ionic and osmotic conditions in gray matter.bioRxiv : the preprint server for biology · 2025Article
- Mapping the microstructure of human cerebral cortex in vivo with diffusion MRI.Communications biology · 2025Article
- In vivo cortical microstructure mapping using high-gradient diffusion MRI accounting for intercompartmental water exchange effects.NeuroImage · 2025Article
- Visualizing cortical laminar architecture in the living human brain using next-generation ultra-high-gradient diffusion MRI.Research square · 2025Article
- 3D MERMAID: 3D Multi-shot enhanced recovery motion artifact insensitive diffusion for submillimeter, multi-shell, and SNR-efficient diffusion imaging.Magnetic resonance in medicine · 2025Article
- Human gray matter microstructure mapped using neurite exchange imaging (NEXI) on a clinical scanner.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Somatosensory-evoked response induces extensive diffusivity and kurtosis changes associated with neural activity in rodents.Imaging neuroscience (Cambridge, Mass.) · 2025Article
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- The Diffusion Exchange Ratio (DEXR): A minimal sampling of diffusion exchange spectroscopy to probe exchange, restriction, and time-dependence.bioRxiv : the preprint server for biology · 2024Article
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6 authors.
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Abstract
Biophysical models of diffusion tailored to quantify gray matter microstructure are gathering increasing interest. The two-compartment Neurite EXchange Imaging (NEXI) model has been proposed recently to account for neurites, extra-cellular space, and exchange across the cell membrane. NEXI parameter estimation requires multi-shell multi-diffusion time data and has so far only been implemented experimentally on animal data collected on a preclinical magnetic resonance imaging (MRI) set-up. In this work, the translation of NEXI to the human cortex in vivo was achieved using a 3 T Connectom MRI system with 300 mT/m gradients, that enables the acquisition of a broad range of b-values (0 - 7.5 ms/µm²) with a window covering short to intermediate diffusion times (20 - 49 ms) suitable for the characteristic exchange times (10 - 50 ms). Microstructure estimates of four model variants: NEXI, NEXI
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