Evidence map›Paper›PMID 40800447›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2024

PET imaging of the serotonin 1A receptor in major depressive disorder: Hierarchical multivariate analysis of [

Granville J Matheson, Francesca Zanderigo, Jeffrey M Miller, Elizabeth A Bartlett, J John Mann, R Todd Ogden

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Granville J MathesonDepartment of Psychiatry, Columbia University, New York, NY, United States.
Francesca ZanderigoDepartment of Psychiatry, Columbia University, New York, NY, United States.
Jeffrey M MillerDepartment of Psychiatry, Columbia University, New York, NY, United States.
Elizabeth A BartlettDepartment of Psychiatry, Columbia University, New York, NY, United States.
J John MannDepartment of Psychiatry, Columbia University, New York, NY, United States.
R Todd OgdenDepartment of Psychiatry, Columbia University, New York, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The serotonin 1A receptor has been linked to both the pathophysiology of major depressive disorder (MDD) and the antidepressant action of serotonin reuptake inhibitors. Most PET studies of the serotonin 1A receptor in MDD used the receptor antagonist radioligand, [carbonyl-

Indexed as

major depressive disorderpharmacokinetic modellingpositron emission tomographyserotonin 1A receptor

Identifiers

PMID40800447
PMCPMC12290790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.