Evidence map›Paper›PMID 40800438›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2024

Unconstrained quantitative magnetization transfer imaging: Disentangling T

Jakob Assländer, Andrew Mao, Elisa Marchetto, Erin S Beck, Francesco La Rosa, Robert W Charlson, Timothy M Shepherd, Sebastian Flassbeck

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Sensitivity of LiteratureNMR in biomedicine · 2026
    Article
  4. Article
  5. Rapid 3D whole-brain high-resolution TMagnetic resonance in medicine · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Magnetization transfer explains most of the TMagnetic resonance in medicine · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Cramér-Rao Bound Optimized Subspace Reconstruction in Quantitative MRI.IEEE transactions on bio-medical engineering · 2025
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jakob AssländerCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Andrew MaoCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Elisa MarchettoCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Erin S BeckCorinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Francesco La RosaCorinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Robert W CharlsonDepartment of Neurology, New York University School of Medicine, New York, NY, United States.
Timothy M ShepherdCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Sebastian FlassbeckCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Riccardo Lattanzi · 2014 to 2026
$19.3M
Medical Scientist Research Service AwardT32GM136573 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SULMAN, ERIK · 2020 to 2024
$6.8M
Quantification of Multi-Compartment T1 Relaxation and Magnetization Transfer in Biological Tissue: From Biophysics to Biomarkers for Multiple SclerosisR01NS131948 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Jakob Asslaender · 2024 to 2026
$1.8M
Development of Multi-Compartment MR-Fingerprinting for Subvoxel Estimation of Quantitative Tissue BiomarkersR21EB027241 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ASSLAENDER, JAKOB, KNOLL, FLORIAN · 2019 to 2020
$462k
Quantitative Magnetization Transfer Imaging for Early Detection of Alzheimer's DiseaseF30AG077794 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MAO, ANDREW · 2022 to 2025
$213k
NIA NIH HHS F30 AG077794NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R21 EB027241NIGMS NIH HHS T32 GM136573NINDS NIH HHS R01 NS131948
6 · The paper itself

Abstract

Since the inception of magnetization transfer (MT) imaging, it has been widely assumed that Henkelman's two spin pools have similar longitudinal relaxation times, which motivated many researchers to constrain them to each other. However, several recent publications reported a

Indexed as

magnetization transferMR fingerprintingmultiple sclerosisparameter mappingqMRIquantitative MRIrelaxometry

Identifiers

PMID40800438
PMCPMC12247553

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.