Evidence map›Paper›PMID 40800275›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2024

Volume electron microscopy in injured rat brain validates white matter microstructure metrics from diffusion MRI.

Ricardo Coronado-Leija, Ali Abdollahzadeh, Hong-Hsi Lee, Santiago Coelho, Benjamin Ades-Aron, Ying Liao, Raimo A Salo, Jussi Tohka, Alejandra Sierra, Dmitry S Novikov and 1 more

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  5. Article
  6. Article
  7. Normal appearing white matter and disability in multiple sclerosis.medRxiv : the preprint server for health sciences · 2025
    Article
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  9. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Ricardo Coronado-LeijaBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Ali AbdollahzadehBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Hong-Hsi LeeAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Santiago CoelhoBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Benjamin Ades-AronBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Ying LiaoBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Raimo A SaloA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Jussi TohkaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Alejandra SierraA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Dmitry S NovikovBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.
Els FieremansBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Riccardo Lattanzi · 2014 to 2026
$19.3M
Mesoscopic Biomarkers of Neurodegeneration with Diffusion MRIR01NS088040 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FIEREMANS, ELS, NOVIKOV, DMITRY S · 2014 to 2023
$5.2M
Random Matrix Theory-Based Noise Removal in MRIR01EB027075 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FIEREMANS, ELS, NOVIKOV, DMITRY S · 2019 to 2022
$2.7M
Revealing tissue microstructure in the brain gray matter in Alzheimer's disease using in vivo high-gradient diffusion MRIDP5OD031854 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HONG HSI · 2021 to 2025
$2.1M
Quantifying Demyelination and Axonal Loss with Diffusion MRIR21NS081230 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FIEREMANS, ELS, KIM, SUNGHEON GENE · 2012 to 2013
$561k
NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R01 EB027075NIH HHS DP5 OD031854NINDS NIH HHS R01 NS088040NINDS NIH HHS R21 NS081230
6 · The paper itself

Abstract

Biophysical modeling of diffusion MRI (dMRI) offers the exciting potential of bridging the gap between the macroscopic MRI resolution and microscopic cellular features, effectively turning the MRI scanner into a noninvasive

Indexed as

3d electron microscopybiophysical modelingdiffusion MRImicrostructuretraumatic brain injurywhite matter

Identifiers

PMID40800275
PMCPMC12272244

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.