Evidence map›Paper›PMID 40800273›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2024

Bridging Huntington's disease research with big data science: Harmonized neuroimaging datasets from multiple studies.

Dorian Pustina, Sandhitsu Das, Dan Rozelle, Hans J Johnson, Rachael I Scahill, Sarah J Tabrizi, Nellie Georgiou-Karistianis, Cristina Sampaio, Andrew Wood

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dorian PustinaCHDI Management, Inc. (the company that manages the scientific activities of CHDI Foundation, Inc.), Princeton, NJ, United States.
Sandhitsu DasPaid Consultant, Rancho BioSciences, Rancho Santa Fe, CA, United States.
Dan RozelleRancho BioSciences, Rancho Santa Fe, CA, United States.
Hans J JohnsonDepartment of Biomedical Engineering, University of Iowa, Iowa City, IA, United States.
Rachael I ScahillHD Research Centre, University College London Queen Square Institute of Neurology, UCL, London, United Kingdom.
Sarah J TabriziHD Research Centre, University College London Queen Square Institute of Neurology, UCL, London, United Kingdom.
Nellie Georgiou-KaristianisSchool of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Melbourne, VIC, Australia.
Cristina SampaioCHDI Management, Inc. (the company that manages the scientific activities of CHDI Foundation, Inc.), Princeton, NJ, United States.
Andrew WoodCHDI Management, Inc. (the company that manages the scientific activities of CHDI Foundation, Inc.), Princeton, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple neuroimaging datasets from Huntington's disease (HD) studies are publicly available, but these datasets are in various formats, omit imaging metadata, and sometimes contain corrupt scans. We have created a platform to curate, harmonize, and distribute neuroimaging datasets from eight different studies: TRACK-HD, TRACKOn-HD, PREDICT-HD, IMAGE-HD, HD-YAS, SHIELD-HD, PEARL-HD, and LONGPDE10. The platform is organized into three conceptual levels to serve the research community with both raw and processed data. Raw data are converted into Brain Imaging Data Structure (BIDS) format, while processed data are obtained from pipelines such as Freesurfer and fmriprep. Studies that had followed the same participants were combined. After combining studies, the final six BIDS datasets include a total of 2,216 participants and 7,073 sessions. We outline tools, principles, and recommendations for future data management in HD research.

Indexed as

clinicalfederationfmrimodelingPETtherapeutic

Identifiers

PMID40800273
PMCPMC12315745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.