Evidence map›Paper›PMID 40800264›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2024

XCP-D: A robust pipeline for the post-processing of fMRI data.

Kahini Mehta, Taylor Salo, Thomas J Madison, Azeez Adebimpe, Danielle S Bassett, Max Bertolero, Matthew Cieslak, Sydney Covitz, Audrey Houghton, Arielle S Keller and 13 more

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

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  11. Benchmarking fMRI Denoising Pipelines.Human brain mapping · 2026
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Kahini MehtaLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Taylor SaloLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Thomas J MadisonMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Azeez AdebimpeLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Danielle S BassettDepartment of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States.
Max BertoleroLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Matthew CieslakLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Sydney CovitzLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Audrey HoughtonMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Arielle S KellerLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Jacob T LundquistMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Audrey LuoLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Oscar Miranda-DominguezMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Steve M NelsonMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Golia ShafieiLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Sheila ShanmuganLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Russell T ShinoharaPenn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Christopher D SmyserDepartments of Neurology, Pediatrics, and Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Valerie J SydnorLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Kimberly B WeldonMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Eric FeczkoMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Damien A FairMasonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States.
Theodore D SatterthwaiteLifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional neuroimaging is an essential tool for neuroscience research. Pre-processing pipelines produce standardized, minimally pre-processed data to support a range of potential analyses. However, post-processing is not similarly standardized. While several options for post-processing exist, they may not support output from different pre-processing pipelines, may have limited documentation, and may not follow generally accepted data organization standards (e.g., Brain Imaging Data Structure (BIDS)). In response, we present XCP-D: a collaborative effort between PennLINC at the University of Pennsylvania and the DCAN lab at the University of Minnesota. XCP-D uses an open development model on GitHub and incorporates continuous integration testing; it is distributed as a Docker container or Apptainer image. XCP-D generates denoised BOLD images and functional derivatives from resting-state data in either NIfTI or CIFTI files following pre-processing with fMRIPrep, HCP, or ABCD-BIDS pipelines. Even prior to its official release, XCP-D has been downloaded >5,000 times from DockerHub. Together, XCP-D facilitates robust, scalable, and reproducible post-processing of fMRI data.

Indexed as

fMRIfunctional connectivitypost-processingresting-statesoftware

Identifiers

PMID40800264
PMCPMC12288603

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.