ArticleJGH open : an open access journal of gastroenterology and hepatology2025
Lymphocyte Fractions as Indicators of T-Helper 1/T-Helper 2 Cytokine Profiles in Inflammatory Bowel Disease.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Lymphocyte Fractions as Indicators of T-Helper 1/T-Helper 2 Cytokine Profiles in Inflammatory Bowel Disease.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
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Authors and funding
12 authors.
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Abstract
Aims: Inflammatory bowel disease is characterized by various cytokine patterns. In this study, we aimed to investigate the markers that can distinguish Th1/Th2 cytokines in patients with inflammatory bowel disease. Methods and Results: In patients with inflammatory bowel disease treated at our hospital, the Th1/Th2 ratio (interferon-γ/interleukin-4 ratio), serum immunoglobulin E level, leucine-rich alpha 2 glycoprotein level, serum amyloid A level, and leukocyte fraction were measured simultaneously, and the relationship between them was examined. We enrolled 108 patients with Crohn's disease and 153 patients with ulcerative colitis. No significant difference was observed in the Th1/Th2 ratio between the ulcerative colitis and Crohn's disease groups. In the inflammatory bowel disease and Crohn's disease groups, the lymphocyte fraction was significantly correlated with the Th1/Th2 ratio ( Conclusions: The lymphocyte fraction may serve as a marker of Th1/Th2 cytokines and could be particularly useful in non-steroid-treated patients.
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