ArticleFrontiers in veterinary science2025
Treats containing cannabidiol, L-tryptophan and
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Demand for stress-reducing products aimed at pets has risen in recent years, demonstrated by an ever-growing market of nutritional and odor-based products. Previous research has demonstrated an effect of Cannabidiol (CBD), L-tryptophan and Methods: A blinded cross-over study was performed in which 54 dogs received a single dose of each treatment two hours prior to exposure to a previously developed stress paradigm (10 min. car travel). A range of behavioural and physiological measures were collected pre/post (plasma CBD levels, serum cortisol) or during (heart rate, heart rate variability, surface temperature, activity, posture, stress-related behaviours, qualitative ratings) the stress paradigm. Results: All treatments resulted in elevated post-test CBD levels in the plasma in comparison to placebo ( Discussion: CBD combined with the blend had a mild stress-reducing effect in dogs. Further exploration of the efficacy of CBD in reducing stress and anxiety, including interactions with different active ingredients and individual differences in absorption and metabolism are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.