ArticleCase reports in women's health2025
Chronic inflammatory demyelinating polyneuropathy complicated by pre-eclampsia progressing to HELLP syndrome and pulmonary embolism: A case report.
Article in Case reports in women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune mediated peripheral neurologic disease characterized by symmetric, ascending progressive limb weakness and paresthesia. It is a rare and diagnostically challenging condition. Pregnancy-induced CIDP is especially rare, with few case series describing treatment courses, pregnancy outcomes and complications. This report concerns a case of a 20-year-old primigravida with CIDP who was initially misdiagnosed with bilateral Bell's palsy. Symptoms progressively worsened to include ascending limb weakness, allodynia, urinary retention and fecal incontinence; she later met criteria for CIDP. Her pregnancy went on to be complicated by prolonged hospitalization and pre-eclampsia; after induction of intravenous immunoglobulin therapy, she developed acute pulmonary embolism and HELLP syndrome, and required emergent C-section delivery. The diagnosis, treatment and management of severe pregnancy complications associated with CIDP are described.
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