ArticleJournal of biological methods2025
Bacterial identification using MALDI-TOF mass spectrometry in positive blood cultures: A pilot study.
Article in Journal of biological methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Early pathogen identification in the bloodstream has long been a key focus for microbiologists and clinicians, given its crucial role in patient management. Matrix-assisted laser desorption ionization-time of flight mass spectrometry has emerged as a valuable tool for the direct and rapid identification of organisms from positive blood cultures. Objective: This study aimed to evaluate the accuracy, productivity, and feasibility of two methods for the rapid detection of bloodstream infections. Methods: Two methods were employed in this study: One based on differential centrifugation and the other using a lysis buffer. Results: The addition of a lysis buffer, sodium dodecyl sulfate (SDS), to the blood culture broth resulted in the identification of a greater number of microorganisms ( Conclusion: The application of SDS into culture broths is user-friendly and can be easily integrated into routine blood culture processing, allowing for species-level identification within hours of a positive BacT/ALERT signal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.