Evidence map›Paper›PMID 40799988›Full record

ArticleMaterials today. Bio2025

Ultrasound-activated bimetallic PtRu alloy nanozymes for synergistic sonodynamic and chemodynamic therapy of multidrug-resistant bacterial infection.

Xiang Zheng, Lingxia Pang, Youpei Wang, Qianlei Zhao, Guoquan Pan, Xiaojun He, Yafeng Liang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiang ZhengPediatric Emergency Department, Zhejiang Provincial Clinical Research Center for Pediatric Precision Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325000, Wenzhou, China.
Lingxia PangFunction Experiment Teaching Center, Wenzhou Medical University, 325000, Wenzhou, China.
Youpei WangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, 325000, Wenzhou, China.
Qianlei ZhaoPediatric Neurology Department, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325000, Wenzhou, China.
Guoquan PanPediatric Intensive Care Unit, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325000, Wenzhou, China.
Xiaojun HeDepartment of Ophthalmology, Peking University First Hospital, Beijing, 100034, China.
Yafeng LiangPediatric Emergency Department, Zhejiang Provincial Clinical Research Center for Pediatric Precision Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325000, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep-seated infections caused by multidrug-resistant (MDR) bacteria, such as pneumonia and abscesses, present significant therapeutic challenges due to their complex pathological microenvironments, which often limit the efficacy of conventional antibiotic treatments. The increasing emergence of MDR bacteria, along with their ability to rapidly acquire resistance, has intensified the need for novel therapeutic strategies. The advancement of nanotechnology has facilitated the development of non-antibiotic-dependent treatment modalities, which are increasingly preferred due to their high efficiency, non-invasiveness, and resistance-free properties. In this study, guided by density functional theory (DFT) predictions, we designed an ultrasound (US)-activated bimetallic Pt

Indexed as

Alloy nanozymesAntibacterial and antibiofilmBacterial pneumoniaSonodynamic/chemodynamic therapyTheoretical calculation

Identifiers

PMID40799988
PMCPMC12341713

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.