Evidence map›Paper›PMID 40799972›Full record

ArticleNeurophotonics2025

Comparison of diffuse correlation spectroscopy, interferometric diffusing wave spectroscopy, and speckle contrast optical spectroscopy for blood flow monitoring.

Joseph B Majeski, Rodrigo M Forti, Sang Hoon Chong, Santosh Aparanji, Mingjun Zhao, Kenneth Abramson, Nithin R Ramachandran, Vivek J Srinivasan, Wesley B Baker, Arjun G Yodh

Abstract read
In one paragraph

Article in Neurophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joseph B MajeskiUniversity of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States.
Rodrigo M FortiUniversity of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0002-8978-2525
Sang Hoon ChongUniversity of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0002-6722-0812
Santosh AparanjiNew York University, Tech4Health Institute, Langone Health, New York City, New York, United States.ORCID https://orcid.org/0009-0004-2459-4322
Mingjun ZhaoNew York University, Tech4Health Institute, Langone Health, New York City, New York, United States.ORCID https://orcid.org/0000-0002-8657-4413
Kenneth AbramsonUniversity of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0002-0781-2648
Nithin R RamachandranUniversity of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0009-0004-3198-7896
Vivek J SrinivasanNew York University, Tech4Health Institute, Langone Health, New York City, New York, United States.ORCID https://orcid.org/0000-0001-9683-1949
Wesley B BakerChildren's Hospital of Philadelphia, Division of Neurology, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0002-3025-6061
Arjun G YodhUniversity of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0003-4744-2706

Funding

Training and DisseminationP41EB015893 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2012 to 2019
$11.3M
TRD3: Data Analytics and Intelligent Systems (AI-ML-DL-Visualization)P41EB032840 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Griffith R. Harsh, Laura Marcu · 2022 to 2026
$6.7M
BRIAN INJURY TRAINING GRANTT32NS043126 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Douglas Hamilton Smith · 2003 to 2026
$5.9M
Achieving specificity in imaging neurodegeneration with visible light Optical Coherence TomographyOT2OD038130 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BALCER, LAURA, SRINIVASAN, VIVEK JAY · 2024 to 2025
$4.8M
True Sub-Micron Ocular Diagnostics with Visible Light Optical Coherence TomographyR01EY031469 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SRINIVASAN, VIVEK JAY · 2020 to 2023
$2.3M
Human Brain Interferometers for Better Blood Flow MonitoringR01EB029747 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SRINIVASAN, VIVEK JAY · 2020 to 2023
$2.2M
Diffuse Optics for Pediatric Hydrocephalus ManagementR01NS113945 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI BAKER, WESLEY · 2020 to 2024
$1.9M
Coherence engineering of a human brain interferometer to quantitatively and specifically measure cerebral blood flowR01EB035762 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Vivek Jay Srinivasan · 2025 to 2026
$1.3M
Development of highly parallelized interferometric near-infrared spectroscopy for the real-time non-invasive measurement of cerebral blood flowR41NS137832 · NINDS · NEURALENZ, INC · PI KHOLIQOV, OYBEK · 2024 to 2024
$499k
NEI NIH HHS R01 EY031469NIBIB NIH HHS P41 EB015893NIBIB NIH HHS P41 EB032840NIBIB NIH HHS R01 EB029747NIBIB NIH HHS R01 EB035762NIH HHS OT2 OD038130NINDS NIH HHS R01 NS113945NINDS NIH HHS R41 NS137832NINDS NIH HHS T32 NS043126
6 · The paper itself

Abstract

Significance: Noninvasive optical measurements of blood flow have many applications. Measurements have been demonstrated with diffuse correlation spectroscopy (DCS), interferometric diffusing wave spectroscopy (iDWS), and speckle contrast optical spectroscopy (SCOS) techniques, but concurrent measurements with all three techniques in the same experiment have not been compared. Aim: We aim to evaluate the comparative strengths and weaknesses of SCOS, iDWS, and DCS methods in controlled experiments. Approach: We performed Results: Conclusions: The experiments demonstrate the equivalency of absolute flow measures from iDWS and DCS and improved precision of pulsatile waveforms from SCOS. These results emphasize the need for rapid development and adoption of iDWS and SCOS.

Indexed as

blood flow monitoringdiffuse correlation spectroscopydiffuse opticsinterferometric diffusing wave spectroscopyspeckle contrast optical spectroscopy

Identifiers

PMID40799972
PMCPMC12340614

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.