Clinicopathological Considerations in the Treatment of Unicystic Adenoid Ameloblastoma in Young Adults: A Clinical Case.

This article presents the case study of a 26-year-old female patient who came to our institute with pain and swelling in the left side of her lower jaw and face that had persisted for over a month. A histological examination of the lesion revealed a cystic odontogenic epithelium with a flat interface between the epithelium and connective tissue. This was accompanied by juxtaepithelial induction and mural proliferation in the form of follicles. The tumour epithelium met the Vickers-Gorlin criteria, and in some areas, the tumour cells were arranged in a plexiform pattern. We also observed regions of degeneration, a dentinoid component, and cells organised in a whorled pattern associated with the dentinoid. The lesion was diagnosed as unicystic adenoid ameloblastoma (UAA). After conservative treatment, the lesion recurred one year later, showing histological features similar to those of the primary lesion. UAA requires meticulous clinical and pathological examination, as well as a tailored management approach, to prevent recurrence and achieve optimal treatment outcomes.