Evidence map›Paper›PMID 40799857›Full record

ArticleCureus2025

An Interesting Case of Anti-Small Ubiquitin-Like Modifier-Activating Enzyme (SAE) Antibody-Positive Dermatomyositis.

Smrithi Suresh, Suresh Kumar, Bhargavi M V, Srinivasan Ramadurai, Rajkumar Mani

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Smrithi SureshGeneral Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Suresh KumarGeneral medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Bhargavi M VGeneral Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Srinivasan RamaduraiGeneral Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Rajkumar ManiGeneral Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatomyositis (DM) is a heterogeneous autoimmune disease characterized by inflammatory involvement of the skin and muscles. Anti-small ubiquitin-like modifier activating enzyme (SAE) antibodies define a rare clinical subtype of DM, often associated with prominent cutaneous findings and systemic features such as dysphagia. This report presents the case of a 45-year-old male with steroid-refractory, anti-SAE-positive DM, highlighting the diagnostic and therapeutic challenges of this condition and underscoring the importance of early recognition and personalized management.

Indexed as

antibodiesautoimmune diseasederrmatomyositisdysphagiamuscle weaknessrituximabsteroid resistance

Identifiers

PMID40799857
PMCPMC12341646

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.