Evidence map›Paper›PMID 40799856›Full record

ArticleCureus2025

Ciprofloxacin and Metronidazole As Rare Culprits of Drug-Induced Immune Thrombocytopenia in the Setting of Diverticulitis Treatment.

Jody W Tai, Ericka H Young, Vivek D Shah, Jarred P Reed

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jody W TaiInternal Medicine, Olive View University of California Los Angeles Medical Center, Los Angeles, USA.
Ericka H YoungInternal Medicine, Olive View University of California Los Angeles Medical Center, Los Angeles, USA.
Vivek D ShahHematology and Medical Oncology, Olive View University of California Los Angeles Medical Center, Los Angeles, USA.
Jarred P ReedOncology, Olive View University of California Los Angeles Medical Center, Los Angeles, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced immune thrombocytopenia (DITP) is a syndrome in which antibodies bind to platelets only in the presence of a drug, leading to platelet destruction. A variety of medications, herbs, vaccines, and foods have been commonly associated with DITP. Here, we present a case of DITP in a 61-year-old female who was receiving two widely prescribed antibiotics, ciprofloxacin and metronidazole, which are not commonly linked to DITP. The patient developed thrombocytopenia within 24 hours of initiating these antibiotics, and her platelet count rapidly normalized following discontinuation of the drugs. Severe thrombocytopenia can lead to life-threatening bleeding; therefore, it is imperative that treating providers rule out alternative causes of thrombocytopenia and promptly discontinue any potential offending agents.

Indexed as

ciprofloxacindiverticulitisdrug-induced thrombocytopeniaimmune thrombocytopeniametronidazole

Identifiers

PMID40799856
PMCPMC12341647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.