Evidence map›Paper›PMID 40799839›Full record

ArticleIEEE control systems letters2024

A Moments-Based Analytical Approach for Cell Size Homeostasis.

César Nieto, Cesar Augusto Vargas-Garcia, Abhyudai Singh

Abstract read
In one paragraph

Article in IEEE control systems letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  8. A GeneralizedbioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

César NietoDepartment of Electrical and Computer Engineering, University of Delaware, Newark, DE 19716 USA.ORCID 0000-0001-6504-4619
Cesar Augusto Vargas-GarciaAGROSAVIA - Corporacion Colombiana de Investigacion Agropecuaria, Mosquera, Cundinamarca 250047, Colombia.ORCID 0000-0002-4286-8882
Abhyudai SinghDepartment of Electrical and Computer Engineering, Biomedical Engineering, Mathematical Sciences, Center of Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19716 USA.ORCID 0000-0002-1451-2838

Funding

Generalized fluctuation test for deciphering phenotypic switching within cell populationsR35GM148351 · NIGMS · UNIVERSITY OF DELAWARE · PI Abhyudai Singh · 2023 to 2026
$1.6M
NIGMS NIH HHS R35 GM148351
6 · The paper itself

Abstract

This contribution explores mechanisms that regulate the dynamics of single-cell size, maintaining equilibrium around a target set point. Using the formalism of Stochastic Hybrid Systems (SHS), we consider continuous exponential growth in cell size (as determined by volume/mass/surface area). This continuous-time evolution is interspersed by cell division events that occur randomly as per a given size-dependent rate, and upon division, only one of the two daughter cells is tracked. We show that a size-independent division rate does not provide cell size homeostasis, in the sense that the variance in cell size increases unboundedly over time. Next, we consider a division rate proportional to cell size that yields the

Indexed as

hybrid systemsstochastic systemsSystems biology

Identifiers

PMID40799839
PMCPMC12342050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.