Evidence map›Paper›PMID 40799743›Full record

ArticleResearch square2025

Effects of Emodepside on Single-Channel Properties of Onchocerca volvulus SLO-1A (BK) Potassium Channels.

Charity Nya Njeshi, Shivani Choudhary, Mark Andrew McHugh, Sudhanva Srinivas Kashyap, Alan Patrick Robertson, Richard John Martin

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Charity Nya NjeshiIowa State University.
Shivani ChoudharyIowa State University.
Mark Andrew McHughIowa State University.
Sudhanva Srinivas KashyapIowa State University.
Alan Patrick RobertsonIowa State University.
Richard John MartinIowa State University.

Funding

RESISTANCE &MODULATION OF LEVAMISOLE RECEPTOR CHANNELSR01AI047194 · NIAID · IOWA STATE UNIVERSITY · PI MARTIN, RICHARD JOHN · 2001 to 2021
$5.8M
Slo-1K channels, TRP-2 channels, emodepside and diethylcarbamazine in FilariaR01AI155413 · NIAID · IOWA STATE UNIVERSITY · PI Richard John Martin · 2020 to 2026
$2.7M
NIAID NIH HHS R01 AI047194NIAID NIH HHS R01 AI155413
6 · The paper itself

Abstract

Background: Control of onchocerciasis (river blindness of humans due to infection with the filarial nematode, Methods: Results: Conclusion: This study successfully expressed

Indexed as

electrophysiologyemodepsideonchocerciasissingle-channel currentsSLO-1Kverruculogen

Identifiers

PMID40799743
PMCPMC12340919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.