Evidence map›Paper›PMID 40799705›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2023

BASIL: A toolbox for perfusion quantification using arterial spin labelling.

Michael A Chappell, Thomas F Kirk, Martin S Craig, Flora A Kennedy McConnell, Moss Y Zhao, Bradley J MacIntosh, Thomas W Okell, Mark W Woolrich

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
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  4. Posterior communicating artery variation is linked to compromised cerebral hemodynamics in middle-aged and older adults.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  5. Article
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  7. Human Cerebral Blood Flow Activity with Diurnal Variation Differentially Correlated with the Suprachiasmatic Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Characterizing pre- and post-operative cerebral blood flow and transit time in pediatric moyamoya patients using multi-delay ASL and DSC MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
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  12. Article
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  14. Observational
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  19. Dynamic BMagnetic resonance in medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael A ChappellSir Peter Mansfield Imaging Center, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Thomas F KirkSir Peter Mansfield Imaging Center, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Martin S CraigSir Peter Mansfield Imaging Center, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Flora A Kennedy McConnellSir Peter Mansfield Imaging Center, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Moss Y ZhaoDepartment of Radiology, Stanford University, Stanford, CA, United States.
Bradley J MacIntoshHurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
Thomas W OkellWellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.
Mark W WoolrichWellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial Spin Labelling (ASL) MRI is now an established non-invasive method to quantify cerebral blood flow and is increasingly being used in a variety of neuroimaging applications. With standard ASL acquisition protocols widely available, there is a growing interest in advanced options that offer added quantitative precision and information about haemodynamics beyond perfusion. In this article, we introduce the BASIL toolbox, a research tool for the analysis of ASL data included within the FMRIB Software Library (FSL), and explain its operation in a variety of typical use cases. BASIL is not offered as a clinical tool, and nor is this work intended to guide the clinical application of ASL. Built around a Bayesian model-based inference algorithm, the toolbox is designed to quantify perfusion and other haemodynamic measures, such as arterial transit times, from a variety of possible ASL input data, particularly exploiting the information available in more advanced multi-delay acquisitions. At its simplest, the BASIL toolbox offers a graphical user interface that provides the analysis options needed by most users; through command line tools, it offers more bespoke options for users needing customised analyses. As part of FSL, the toolbox exploits a range of complementary neuroimaging analysis tools so that ASL data can be easily integrated into neuroimaging studies and used alongside other modalities.

Indexed as

arterial spin labellingarterial transit timecerebral blood flowperfusionvariational Bayesian inference

Identifiers

PMID40799705
PMCPMC12007520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.