Evidence map›Paper›PMID 40799674›Full record

ArticleMRS bulletin2023

Three-dimensional and four-dimensional printing in otolaryngology.

Irene Chiesa, Carmelo De Maria, Giovanni Vozzi, Riccardo Gottardi

Abstract read
In one paragraph

Article in MRS bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Irene ChiesaDepartment of Information Engineering and Research Center E. Piaggio, University of Pisa, Pisa, Italy.
Carmelo De MariaDepartment of Information Engineering and Research Center E. Piaggio, University of Pisa, Pisa, Italy.
Giovanni VozziDepartment of Information Engineering and Research Center E. Piaggio, University of Pisa, Pisa, Italy.
Riccardo GottardiDepartment of Surgery, Division of Otolaryngology, Children's Hospital of Philadelphia, Philadelphia, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, USA; Department of Pediatrics, Division of Pulmonary Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA; Department of Otorhinolaryngology, Division of Pulmonary Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA; Ri.MED Foundation, Palermo, Italy.ORCID 0000-0001-8040-5531

Funding

Decellularized cartilage and progenitor cells for laryngotracheal reconstructionR56HL164536 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI GOTTARDI, RICCARDO · 2022 to 2022
$617k
Bioengineered grafts for laryngotracheal reconstructionR21HL159521 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI GOTTARDI, RICCARDO · 2022 to 2023
$484k
NHLBI NIH HHS R21 HL159521NHLBI NIH HHS R56 HL164536
6 · The paper itself

Abstract

Each year, thousands of patients deal with ear, nose, and throat disorders that can be life threatening such as tracheal stenosis, or impact the psychosocial well-being, such as microtia. These often require surgical intervention using autologous or allogenic grafts. Tissue engineering represents an exciting alternative to substitute the use of human tissues, by fabricating living bioartificial constructs using three-dimensional scaffolds that incorporate or support human cells that can proliferate and mature. The complex geometries of ear, nose, and throat call for advanced fabrication techniques such as bioprinting, which leverages additive manufacturing to fabricate patient-specific scaffolds with a high design freedom and repeatability. Here, we will provide a comprehensive overview on the use of bioprinting technologies to address specific challenges in otolaryngology, with relevant examples from recent literature.

Identifiers

PMID40799674
PMCPMC12341431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.