ArticleFrontiers in immunology2025
The predictive value of NLR, SII, and complement 3 in treatment response for systemic lupus erythematosus with immune thrombocytopenia.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Correlation Between Systemic Inflammation Response Index and Systemic Immune-Inflammation Index and Disease Activity of Lupus Nephritis in Children.Children (Basel, Switzerland) · 2026Article
- Application Value of Blood Routine-Derived Indices for the Evaluation of Disease Activity in Systemic Lupus Erythematosus.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2026Article
- Primary Sjögren's syndrome-associated immune thrombocytopenia: from pathogenesis to treatment.Frontiers in immunology · 2026Review
- Association between 12 composite inflammatory indices and postoperative complications in colorectal cancer surgery: a two-center retrospective study.Frontiers in oncology · 2026Article
- Blood-Count-Derived Inflammatory Biomarkers and Characterization of Super-Responder Profile in Psoriatic Patients Receiving Biological Treatment: A Single-Center Study.International journal of molecular sciences · 2025Article
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4 authors.
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Abstract
Objective: To evaluate the predictive value of systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and complement 3 in the therapeutic outcomes of systemic lupus erythematosus-associated immune thrombocytopenia (SLE-ITP). Methods: Clinical data from 72 patients diagnosed with SLE-ITP and admitted to the Affiliated Central Hospital of Dalian University of Technology between January 2013 and September 2024 were collected and analyzed. Associations between therapeutic outcomes and clinical characteristics, as well as laboratory findings including SII and NLR, were evaluated systematically. Results: The patients achieved complete remission (CR) 32 (44.4%), partial remission (PR) 19 (26.4%), and no remission (NR) 21 (29.2%). SII exhibited statistically significant differences among the three groups ( Conclusion: The combined predictive model significantly enhances the predictive efficacy for SLE-ITP treatment outcomes compared to individual indicators.
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