Evidence map›Paper›PMID 40799574›Full record

ArticlebioRxiv : the preprint server for biology2025

Autophagy functions in lung macrophages and dendritic cells to regulate allergen-dependent inflammatory responses.

Neha Dubey, Reilly Woodson, Skyler V Hendrix, Anne L Rosen, Rachel L Kinsella, Samuel R McKee, Marick Starick, Nicole Rivera-Espinal, Sumanta K Naik, Asya Smirnov and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Neha DubeyDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0009-0005-1581-9099
Reilly WoodsonDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Skyler V HendrixDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Anne L RosenDivision of Allergy and Immunology, Department of Medicine and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Rachel L KinsellaDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Samuel R McKeeDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Marick StarickDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Nicole Rivera-EspinalDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Sumanta K NaikDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-4499-0811
Asya SmirnovDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Darren KreamalmeyerDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Andrew L KauDivision of Allergy and Immunology, Department of Medicine and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-9386-3766
Christina L StallingsDepartment of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-2747-5618

Funding

RP5: Chemical proteomic discovery of small-molecule probes for autophagy proteinsU19AI142784 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VIRGIN, HERBERT W · 2019 to 2023
$36.9M
TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4M
Autophagy proteins in the immune response to Mycobacterium tuberculosis infectionR01AI132697 · NIAID · WASHINGTON UNIVERSITY · PI STALLINGS, CHRISTINA LEIGH · 2019 to 2023
$2.4M
NIAID NIH HHS R01 AI132697NIAID NIH HHS U19 AI142784NIGMS NIH HHS T32 GM007067
6 · The paper itself

Abstract

Asthma affects 260 million people worldwide, with severe asthma cases that are associated with T

Indexed as

allergyasthmaautophagyeosinophilsinflammationneutrophilsT cellsTH17

Identifiers

PMID40799574
PMCPMC12340803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.