Evidence map›Paper›PMID 40799537›Full record

ArticlebioRxiv : the preprint server for biology2025

Loss of

Takehiro Kado, Shivangi, Jake Jordan, Joel S Freundlich, M Sloan Siegrist, Yasu S Morita

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takehiro KadoDepartment of Biology, Missouri State University, 901 South National Avenue, Springfield, MO 65897.ORCID 0000-0001-5419-6123
ShivangiDepartment of pharmacology, Physiology, and Neuroscience, New Jersey Medical School, Rutgers University, Newark, NJ 07103.
Jake JordanDepartment of Biology, Missouri State University, 901 South National Avenue, Springfield, MO 65897.
Joel S FreundlichDepartment of pharmacology, Physiology, and Neuroscience, New Jersey Medical School, Rutgers University, Newark, NJ 07103.
M Sloan SiegristDepartment of Microbiology, University of Massachusetts Amherst, 639 North Pleasant Street, Amherst, MA 01003.ORCID 0000-0002-8232-3246
Yasu S MoritaDepartment of Microbiology, University of Massachusetts Amherst, 639 North Pleasant Street, Amherst, MA 01003.ORCID 0000-0002-4514-9242

Funding

Therapeutics for drug-resistant bacteria: aryl myxopyronins and arylalkylcarboxamido phloroglucinolsU19AI142731 · NIAID · HACKENSACK UNIVERSITY MEDICAL CENTER · PI DICK, THOMAS · 2019 to 2023
$33.9M
Chemical detection of Mycobacterium tuberculosis growth and antibiotic response during infectionDP2AI138238 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI SIEGRIST, MARY SLOAN · 2017 to 2017
$2.3M
Spatial organization of mycobacterial cell wall biosynthesisR21AI144748 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI MORITA, YASU S, SIEGRIST, MARY SLOAN · 2019 to 2020
$423k
NIAID NIH HHS DP2 AI138238NIAID NIH HHS R21 AI144748NIAID NIH HHS U19 AI142731
6 · The paper itself

Abstract

The mycomembrane of mycobacteria, composed primarily of long-chain mycolic acids, is critical for cell survival, structural integrity, and resistance to environmental stress, yet its underlying synthesis mechanisms remain incompletely understood. This study investigates the role of Ag85A, a key enzyme in mycomembrane synthesis, in regulating plasma membrane domains and cell envelope organization in

Indexed as

Antigen 85AMembrane domainMembrane permeabilityMycobacteriaMycolic acids

Identifiers

PMID40799537
PMCPMC12340856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.