Evidence map›Paper›PMID 40799506›Full record

ArticleThe Lancet regional health. Europe2025

Clinical presentation, management and outcome of 11,132 patients with liposarcoma patients: a population-based study from the NETSARC+ registry.

Jean-Yves Blay, Maud Toulmonde, Thibaud Valentin, Nelly Firmin, Sarah Watson, Florence Duffaud, Emmanuelle Bompas, Maria Rios, Mikael Ropars, Philippe Anract and 39 more

Abstract read
In one paragraph

Article in The Lancet regional health. Europe, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors.

Jean-Yves BlayDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Maud ToulmondeDepartments of Medical & Surgical Oncology, Institut Bergonié, Bordeaux, France.
Thibaud ValentinDepartment of Medical Oncology, Institut Claudius Regaud, & IUCT Oncopole Toulouse, France.
Nelly FirminDepartment of Medical & Surgical & Radiotherapy Oncology ICM, Montpellier, France.
Sarah WatsonDepartments of Medical & Surgical Oncology, Institut Curie, Paris, France.
Florence DuffaudDepartment of Medical Oncology, La Timone University Hospital, Marseille, France.
Emmanuelle BompasDepartment of Medical Oncology, Centre René Gauducheau, Nantes St. Herblain, France.
Maria RiosDepartment of Medical Oncology, Centre Alexis Vautrin, Vandoeuvre-lès-Nancy, France.
Mikael RoparsDepartment of Orthopedics, CHU Rennes, France.
Philippe AnractDepartment of Medical Oncology, Cochin Hospital, Paris, France.
Armelle DufresneDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Justine GantzerICANS & CHU Strasbourg, Strasbourg, France.
Louis-Romée Le NailCHU Tours, Tours, France.
Esma SaadaCentre Antoine Lacassagne, Nice, France.
Alice HervieuCentre George-Francois Leclerc, Dijon, France.
Francois BertucciInstitut Paoli-Calmette, Marseille, France.
Pascale Dubray-LongerasCentre Jean Perrin, Clermont Ferrand, France.
Vincent CrennCHU Nantes, Nantes, France.
Christophe PerrinCentre Eugene Marquis, Rennes, France.
Pauline SoibinetInstitut Jean Godinot, Reims, France.
Benjamin VerretDepartments of Medicine & Surgery, Gustave Roussy Cancer Campus, Villejuif, France.
Antoine ItalianoDepartments of Medical & Surgical Oncology, Institut Bergonié, Bordeaux, France.
Gauthier DecanterDepartment of Medical Oncology, Centre Oscar Lambret, Lille, France.
Gwenael FerronDepartment of Medical Oncology, Institut Claudius Regaud, & IUCT Oncopole Toulouse, France.
Sebastien CarrereDepartment of Medical & Surgical & Radiotherapy Oncology ICM, Montpellier, France.
Sylvie BonvalotDepartments of Medical & Surgical Oncology, Institut Curie, Paris, France.
Mehdi BrahmiDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Clemence HenonDepartments of Medicine & Surgery, Gustave Roussy Cancer Campus, Villejuif, France.
Mariella Spalato-CerusoDepartments of Medical & Surgical Oncology, Institut Bergonié, Bordeaux, France.
Loic LebellecDepartment of Medical Oncology, Centre Oscar Lambret, Lille, France.
Anne DucassouDepartment of Medical Oncology, Institut Claudius Regaud, & IUCT Oncopole Toulouse, France.
Julien Colard-ThomasDepartment of Medical & Surgical & Radiotherapy Oncology ICM, Montpellier, France.
Sophie Piperno-NeumannDepartments of Medical & Surgical Oncology, Institut Curie, Paris, France.
Jean-Camille MatteiDepartment of Medical Oncology, La Timone University Hospital, Marseille, France.
Francois GouinDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Mathieu FaronDepartments of Medicine & Surgery, Gustave Roussy Cancer Campus, Villejuif, France.
Thomas RyckewaertDepartment of Medical Oncology, Centre Oscar Lambret, Lille, France.
Pierre MeeusDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Charles HonoréDepartments of Medicine & Surgery, Gustave Roussy Cancer Campus, Villejuif, France.
François Le LoarerDepartments of Medical & Surgical Oncology, Institut Bergonié, Bordeaux, France.
Jean-Michel CoindreDepartments of Medical & Surgical Oncology, Institut Bergonié, Bordeaux, France.
Carine NgoDepartments of Medicine & Surgery, Gustave Roussy Cancer Campus, Villejuif, France.
Alexandra MeurgeyDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Marie KaranianDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Claire Chemin-AiriauDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Françoise DucimetiereDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Magali MorelleDepartments of Medical & Surgical Oncology, Centre Léon Bérard & Université Claude Bernard, Lyon, France.
Nicolas PenelDepartment of Medical Oncology, Centre Oscar Lambret, Lille, France.
Axel Le CesneDepartments of Medicine & Surgery, Gustave Roussy Cancer Campus, Villejuif, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Liposarcomas (LPS) are among the most common sarcomas, but gather a diversity of rare to ultrarare molecular subtypes whose presentations and natural histories are partially characterized. The aim of the work was to describe the presentation and outcome of the different LPS histotypes from the NETSARC+ registry. Methods: NETSARC+ (netsarc.org) is a network of 26 reference sarcoma centers with specialized multidisciplinary tumor boards (MDTB), funded by the French INCA since 2010 aiming to improve the quality of care of sarcoma patients. Patients' characteristics, treatment and outcomes are collected in a nationwide database. This work describes the outcome of all LPS confirmed by central review pathology review and integrated between 2010 and 2023 in the NETSARC+ database. Findings: 11,132 liposarcomas are included in the database for an estimated incidence of 11.5/10 Interpretation: In this nationwide series of pathology-confirmed LPS, the clinical presentation, management and survival of histotypes are very different with age-related sex differences favoring women >50. DDLPS is the subtype with the worse prognosis. Funding: This work was supported by the following grants: NetSARC+ (INCA), RREPS (INCA), RESOS (INCA), INTERSARC+ (INCA), LabEx DEvweCAN (ANR-10-LABX-0061), LYriCAN+ (INCa-DGOS-INSERM-ITMO cancer_18,003), Ligue Nationale contre le Cancer, Ligue Contre le Cancer (Comité de l'Ain), Fondation ARC, and EURACAN (EU project 739521).

Indexed as

LiposarcomasNatural historyNetworkReference centersSarcomaSurvival

Identifiers

PMID40799506
PMCPMC12336835

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.