Evidence map›Paper›PMID 40799502›Full record

ReviewClinical Medicine Insights. Oncology2025

Application of Cord Blood-Derived Exosomes in Tumor Prevention and Treatment.

Chen Huang, Yongsheng Li, Baozhong Zhang, Yukuan Tang, Yuyang Huang, Wei Wei

Abstract readReview
In one paragraph

Review in Clinical Medicine Insights. Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chen HuangMinimally Invasive Intervention Department, The Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou, China.
Yongsheng LiScientific Research Center, Guangdong Cord Blood Bank, Guangzhou, China.ORCID https://orcid.org/0000-0002-0285-0493
Baozhong ZhangDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Yukuan TangMinimally Invasive Intervention Department, The Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou, China.
Yuyang HuangDepartment of Bone, Joint and Sports Medicine, The Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou, China.
Wei WeiScientific Research Center, Guangdong Cord Blood Bank, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eradication of tumors remains a critical and challenging issue in medical research. Exosomes (EXOs) derived from various sources have garnered increasing attention in the field of tumor therapy. Among these, cord blood (CB)-derived EXOs may offer unique advantages in combating tumors due to the distinctive properties of CB. This narrative review examines the current application status of CB-derived EXOs in tumor prevention and treatment: in the context of tumor treatment, it focuses on their direct therapeutic application and their use as drug carriers; regarding tumor prevention, it explores their application in cancer vaccines. In addition, it also reviews the specific components of CB from which these EXOs are derived, their particle sizes, characteristic proteins, and the types of tumors to which they have been primarily applied for prevention and treatment. In conclusion, we believe that CB-derived EXOs hold substantial potential for effective tumor prevention and treatment and are likely to emerge as a prominent area of research in the future.

Indexed as

cancercancer vaccineCord blooddrug carrierexosometumor

Identifiers

PMID40799502
PMCPMC12340371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.