Evidence map›Paper›PMID 40799454›Full record

ArticleTranslational lung cancer research2025

Minimally invasive

Paula Duarte D'Ambrosio, Rachid Eduardo Noleto da Nobrega Oliveira, Marcelo Albuquerque Barbosa Martins, Isabella Cabianca Moriguchi Caetano Salvador, Luiza Gonzalez de Andrade, Ricardo Mingarini Terra, Paulo Manuel Pêgo-Fernandes, José Ribas Milanez Campos

Abstract read
In one paragraph

Article in Translational lung cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. RoboticJournal of thoracic disease · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paula Duarte D'AmbrosioDepartment of Thoracic Surgery, Hospital das Clinicas de Sao Paulo, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
Rachid Eduardo Noleto da Nobrega OliveiraDepartment of Thoracic Surgery, Barretos Cancer Center, São Paulo, SP, Brazil.
Marcelo Albuquerque Barbosa MartinsFederal University Ouro Preto, Minas Gerais, Brazil.
Isabella Cabianca Moriguchi Caetano SalvadorUniversity Anhembi Morumbi, São Paulo, SP, Brazil.
Luiza Gonzalez de AndradeUniversity Santo Amaro, São Paulo, SP, Brazil.
Ricardo Mingarini TerraDepartment of Thoracic Surgery, Hospital das Clinicas de Sao Paulo, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
Paulo Manuel Pêgo-FernandesInstituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
José Ribas Milanez CamposDepartment of Thoracic Surgery, Hospital das Clinicas de Sao Paulo, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Minimally invasive chest wall resection (MICWR) has emerged as an alternative to open chest wall resection (OCWR) for lung cancer. This meta-analysis aims to compare perioperative outcomes between MICWR and OCWR in order to evaluate the safety and feasibility of the minimally invasive approach. Methods: A systematic search of PubMed, Embase, and Cochrane Library was conducted until January 20, 2025, for studies comparing MICWR and OCWR in adult patients with non-small cell lung cancer (NSCLC). The effect measures included odds ratios (ORs) for binary outcomes and mean differences (MDs) for continuous outcomes. Statistical analysis was performed using random-effects models. Heterogeneity was assessed with I Results: Three retrospective studies comprising 2,973 patients were included, with 26.3% undergoing MICWR and 73.7% undergoing OCWR. No significant differences were found in overall mortality [OR 1.12; 95% confidence interval (CI): 0.95 to 1.32; P=0.17; I Conclusions: MICWR offers comparable oncologic outcomes to OCWR while reducing postoperative complications. It may also shorten LOS in selected patients. However, evidence is limited to retrospective studies, warranting prospective trials to confirm these findings and define optimal criteria.

Indexed as

chest wall resection (CWR)minimally invasive surgery (MIS)Non-small cell lung cancer (NSCLC)robotic-assisted thoracic surgery (RATS)video-assisted thoracoscopic surgery (VATS)

Identifiers

PMID40799454
PMCPMC12337056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.