Evidence map›Paper›PMID 40799356›Full record

ArticleFrontiers in musculoskeletal disorders2024

Elastic modulus of cadaveric acetabular labrum correlates with ultrashort echo time (UTE) apparent spin-spin (T2*) and spin-lattice (T1) relaxation times.

Dina Moazamian, Takehito Hananouchi, Hamid Reza Shaterian Mohammadi, Seyed Alireza Tayarani Hajian, Erik W Dorthe, Darryl D'Lima, Yajun Ma, Saeed Jerban

Abstract read
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In one paragraph

Article in Frontiers in musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Dina MoazamianDepartment of Radiology, University of California San Diego, San Diego, CA 92093, USA.
Takehito HananouchiDepartment of Mechanical Engineering, Hiroshima University, JP.
Hamid Reza Shaterian MohammadiDepartment of Radiology, University of California San Diego, San Diego, CA 92093, USA.
Seyed Alireza Tayarani HajianDepartment of Pathology, University of California San Diego, San Diego, CA 92093, USA.
Erik W DortheShiley Center for Orthopedic Research and Education at Scripps Clinic, La Jolla, CA 92037, USA.
Darryl D'LimaShiley Center for Orthopedic Research and Education at Scripps Clinic, La Jolla, CA 92037, USA.
Yajun MaDepartment of Radiology, University of California San Diego, San Diego, CA 92093, USA.
Saeed JerbanDepartment of Radiology, University of California San Diego, San Diego, CA 92093, USA.

Funding

Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
Knee evaluation under mechanical loading by cones ultrashort echo time MR imagingK01AR080257 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI saeed jerban · 2022 to 2026
$602k
NIAMS NIH HHS K01 AR080257NIAMS NIH HHS R01 AR079484
6 · The paper itself

Abstract

Introduction: The acetabulum labrum plays a critical role in hip function. Medical imaging techniques for detecting labral degeneration may help improve our knowledge of its role in hip osteoarthritis (OA). This study aimed to explore the correlation between the mechanical properties of the acetabulum labrum and ultrashort echo time (UTE) MRI properties. Material and Method: Acetabular labrum specimens were dissected from 12 fresh-frozen human cadaveric hip joints (64.6±11.6 years old at the time of death, 7 female). UTE Cones sequences were used to measure apparent spin-spin (T2*) and spin-lattice (T1) relaxation times using a knee coil at 3T in a clinical MR scanner. The stiffness and the elastic modulus (E) of the specimens were measured before MRI scans using uniaxial tensile tests. Spearman's rank correlation coefficients of UTE-T2* and -T1 with their mechanical properties of them were calculated. Results: The human labrum specimen elastic modulus showed a significant inverse correlation with UTE-T2* (R=-0.67, P<0.05) and with UTE-T1 (R=-0.56, P=0.05). The stiffness of the specimens showed significant inverse correlations with UTE-T2* (R=-0.53, P=0.05) and UTE-T1 (R=-0.63, P=0.02). Conclusion: This study highlighted the potential of UTE-MRI techniques for the mechanical assessment of the acetabular labrum. UTE-MRI may improve labrum degeneration detection and monitoring, which requires further investigations.

Indexed as

acetabular labrummechanical propertiesosteoarthritisquantitative MRIUTE

Identifiers

PMID40799356
PMCPMC12341470

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