ArticleFrontiers in oncology2025
Imaging features of pancreatic extragastrointestinal stromal tumors: a case report and literature review.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Diagnostic algorithm for the imaging evaluation of a solid pancreatic mass: is it malignant?Abdominal radiology (New York) · 2026Review
- Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Pancreatic extra-gastrointestinal stromal tumors (pEGISTs) are exceedingly rare, accounting for less than 5% of all extra-gastrointestinal stromal tumors (EGISTs). We report a case involving a 62-year-old woman who presented with a hypervascular pancreatic mass. Postoperative histopathological examination confirmed the diagnosis of a gastrointestinal stromal tumor (GIST). The neoplastic cells exhibited a spindle-shaped morphology without evident necrosis on histologic sections. Immunohistochemical analysis demonstrated strong, diffuse positivity for CD117, DOG-1, and CD34. Notably, the imaging characteristics of this pEGISTs displayed several distinctive features, including intralesional "island-like" enhancement, peripheral nodular enhancement, and prominent vascular "staghorn" patterns. Although histopathology remains the gold standard for definitive diagnosis of pEGISTs, correlating clinical presentation with these unique radiologic features can substantially improve diagnostic accuracy for radiologists. Additionally, we provide a comprehensive review and discussion of the current literature on the clinical and imaging hallmarks of pEGISTs.
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