Evidence map›Paper›PMID 40799239›Full record

ArticleFrontiers in oncology2025

Dosimetric analysis of orthogonal collimator configuration in volumetric modulated arc therapy planning: a comparative study.

Xin Huang, Chenlei Guo, Shuangtong Liu, Kuo Men, Hui Wang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xin Huang *Department of Oncology, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.
Chenlei Guo *Department of Radiation Oncology, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shuangtong Liu *Department of Oncology, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.
Kuo MenDepartment of Radiation Oncology, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hui WangDepartment of Oncology, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In volumetric modulated arc therapy (VMAT), collimator angle selection impacts dose distribution and plan quality. Conventional VMAT plans use dual arcs with collimators set at 0˚. This study explores the dosimetric effects of using orthogonal collimator angles (0˚ and 90˚) in dual-arc VMAT. Methods: Sixty patients with head and neck, thoracic, and abdominal tumors were analyzed. Two VMAT plans were generated: Plan A (0˚ collimator angle) and Plan B (0˚ and 90˚ collimator angles). Dosimetric endpoints included conformity index (CI), gradient measure (GM), homogeneity index (HI), dose to organs at risk (OARs), mean dose to normal tissues (D Results: Plan B improved dosimetric outcomes over Plan A. HI decreased by 0.03 in the rectum, 0.01 in the breast, and 0.01 in the larynx. GM decreased by 0.15 cm in the rectum, 0.05 cm in the breast, and 0.01 cm in the larynx. OAR doses were reduced across sites, with notable decreases in the bladder (-4.62 Gy), left anterior descending artery (-3.99 Gy), and spinal cord (-1.79 Gy). D Conclusion: Incorporating orthogonal collimator angles (0˚ and 90˚) in dual-arc VMAT enhances dose conformity and spares OARs without compromising target coverage or delivery accuracy. This approach is clinically applicable with minimal workflow changes.

Indexed as

dose conformity and homogeneityorthogonal collimator anglesradiotherapyradiotherapy treatment planningvolumetric modulated arc therapy

Identifiers

PMID40799239
PMCPMC12340999

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