ArticleContemporary clinical dentistry
CD105 as a Marker of Angiogenesis in Oral Squamous Cell Carcinoma - An Immunohistochemical Study.
Article in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Prognostic Significance of CD105-Assessed Angiogenesis in Relation to Survival and Clinicopathological Features of Oral Squamous Cell Carcinoma.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026Article
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Authors and funding
3 authors.
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Abstract
Background: Oral squamous cell carcinoma (OSCC) is the most prevalent carcinoma of the head-and-neck region. Despite advanced tissue diagnosis, the survival period remains at 5 years. New molecular and cell markers are under investigation to improve survival rate. Objective: The objective of this study was to assess angiogenic activity by analyzing CD105 microvascular density (MVD) count in different histologic grades of OSCC. Subjects and Methods: Sixty samples are categorized into four groups. Immunohistochemical method with anti-CD105 was used for analyzing MVD. Results: The mean count of MVD is higher in OSCC than in normal mucosa and also significant among different histologic grades. A highly significant correlation is observed among different groups of OSCC samples. Conclusion: CD105 is a predictive marker for neoangiogenesis in OSCC.
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