Evidence map›Paper›PMID 40798975›Full record

ReviewCardiovascular & hematological disorders drug targets2026

Spontaneous Lingual Bleeding and Intracerebral Hemorrhage in a Young Adult with Immune Thrombocytopenia (ITP): A Rare Case Report and Brief Recent Update on Treatment.

Jitendra Singh, Anju Dinkar, Nilesh Kumar, Kailash Kumar, Ravi Ranjan, Isha Atam

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In one paragraph

Review in Cardiovascular & hematological disorders drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jitendra SinghDepartment of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.ORCID 0000-0002-4928-5591
Anju DinkarDepartment of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.ORCID 0000-0003-2297-444X
Nilesh KumarDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Kailash KumarDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Ravi RanjanDepartment of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Isha AtamDepartment of Physiology, King George`s Medical University, Lucknow, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImmune thrombocytopenia (ITP) is an autoimmune condition characterized by reduced platelet counts due to increased peripheral destruction and impaired platelet generation. An estimated incidence of ITP is 2 to 5 cases per 100,000 individuals in the general population. While mucocutaneous bleeding is common, life-threatening complications, such as spontaneous lingual hematoma and intracerebral hemorrhage (ICH), are extremely rare. Rapid progression of lingual haematomas might compromise airway function and necessitate immediate medical intervention. It is well established that most patients with ITP respond to first-line therapy; however, severe bleeding events, such as intracerebral hemorrhage, occur in less than 1% of cases and are associated with significant morbidity and mortality. CASE PRESENTATION: A 21-year-old male with a 6-month history of chronic ITP and poor compliance with therapy presented with a 2-day history of progressive reddish discoloration and swelling of the tongue. The clinical examination revealed stable vital signs and a remarkable general and systemic evaluation. The relevant blood routine showed a critically low platelet count at 8×10

conclusionThe present case emphasizes the rarely yet life-threatening complication of inadequately managed ITP, such as spontaneous lingual hematoma and intracranial haemorrhage. It highlights the vital significance of therapy adherence and timely interdisciplinary intervention to avert disastrous consequences. Timely detection and intervention are crucial for positive outcomes in these intricate cases.

Indexed as

Cerebral HemorrhageHemorrhagePurpura, Thrombocytopenic, IdiopathicHumansMaleYoung Adultcorticosteroidseltrombopaghematologic disorderintracranial hemorrhagemucocutaneous bleedingPlatelets

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.