Evidence map›Paper›PMID 40798915›Full record

ArticleJournal of pediatric gastroenterology and nutrition2025

Pediatric endoscopic mucosal resection: A 10-year single-center experience.

Brett J Hoskins, Jared M Grabau, Douglas K Rex

Abstract read
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Pediatric endoscopic mucosal resection: A 10-year single-center experience.Journal of pediatric gastroenterology and nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brett J HoskinsDepartment of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, Riley Hospital for Children at IU Health, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0003-3048-5662
Jared M GrabauDepartment of Medicine, Marian University Tom and Julie Wood College of Osteopathic Medicine, Indianapolis, Indiana, USA.
Douglas K RexDepartment of Medicine, Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Funding

None
6 · The paper itself

Abstract

objectivesEndoscopic mucosal resection (EMR) is well established in adult gastroenterology but remains underutilized in pediatrics due to limited data, training opportunities, and equipment. This study presents a 10-year, single-center experience with conventional hot and cold snare EMR, band-assisted (B-EMR), and underwater EMR (U-EMR) techniques in pediatric patients.

methodsA retrospective review was conducted of all EMR procedures performed in patients under 21 years of age between 2015 and 2025 at a tertiary care children's hospital. Data on patient demographics, lesion characteristics, procedural details, pathology, and outcomes were collected and analyzed descriptively.

resultsTwenty EMRs were performed in 18 patients (mean age 17.1 years, range 3-20). The most common underlying diagnoses included familial adenomatous polyposis (n = 7), sporadic mucosal polyps (n = 4), subepithelial lesions (n = 4), juvenile polyposis syndrome (n = 2), Peutz-Jeghers syndrome (n = 1), and Lynch syndrome (n = 1). Lesions ranged from 6 to 80 mm and were located throughout the gastrointestinal tract, most commonly in the colon (n = 9), duodenum (n = 5), and esophagus (n = 3). Techniques included hot snare EMR (n = 9), cold snare EMR (n = 6), B-EMR (n = 4), and U-EMR (n = 1). Complete resection was achieved in 95% of cases, with one incomplete resection requiring surgical management for adenocarcinoma. B-EMR was safely applied to subepithelial lesions. No delayed complications occurred.

conclusionsEMR is feasible, safe, and effective in pediatric patients for both mucosal and subepithelial lesions. Broader adoption in pediatric practice will require expanded training, multidisciplinary collaboration, and development of pediatric-specific guidelines. These findings support EMR as a valuable therapeutic option in complex pediatric gastrointestinal disease.

Indexed as

Endoscopic Mucosal ResectionIntestinal MucosaAdolescentChildChild, PreschoolFemaleHumansMaleRetrospective StudiesTreatment OutcomeYoung Adultconventional EMRpediatric endoscopypolypectomysubmucosal injection

Identifiers

PMID40798915
PMCPMC12580460

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.