Evidence map›Paper›PMID 40797352›Full record

ArticleHuman vaccines & immunotherapeutics2025

Assessing barriers and facilitators of attitudes toward seasonal influenza vaccination among pregnant women using the Health Belief Model.

Fang Huang, Jingjing Zhu, Jing Qiu, Juan Li, Yuting Liao, Zhi Li, Zhuoying Huang, Xiang Guo, Xiaodong Sun

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fang HuangInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Jingjing ZhuSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jing QiuInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Juan LiInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Yuting LiaoInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Zhi LiInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Zhuoying HuangInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Xiang GuoInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.ORCID 0000-0002-2727-4066
Xiaodong SunInstitute of Immunization, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnant women are at elevated risk of severe influenza-related complications and maternal influenza vaccination protects mothers and infants. Nevertheless, the global maternal influenza vaccination rates remain critically low. This cross-sectional survey, conducted in Shanghai during 2023-2024, applied the Health Belief Model (HBM) to evaluate the attitudes and determinants of seasonal influenza vaccination among 3219 pregnant women. Only 10.9% (351/3219) accepted the vaccination, while 89.1% (1851/3219) declined, including 35.4% (1017/3219) who expressed uncertainty. Key facilitators of acceptance included higher education (graduate degree and above: adjusted odds ratio (aOR) = 2.49) and a greater total influenza knowledge score (aOR = 1.07). Strong HBM constructs, including perceived susceptibility (aOR = 1.53), perceived severity (aOR = 1.66), and belief in vaccine benefit (aOR = 2.55) significantly predicted vaccine uptake. The most influential factor was cues to action (aOR = 8.55). Conversely, safety concerns for maternal and fetal health dominated hesitancy, overshadowing other barriers. As the first HBM-based study to assess the attitude to influenza vaccination among pregnant women in China, these findings revealed low baseline awareness and confidence among Shanghai's population of pregnant women. This study highlighted an urgent need to strengthen provider-patient communication to amplify "cues to action," and integrated vaccination advocacy into routine prenatal care. Addressing these barriers could align vaccination rates with global maternal health priorities, leveraging dual protection for mothers and infants.

Indexed as

Health Belief ModelHealth Knowledge, Attitudes, PracticeInfluenza, HumanInfluenza VaccinesPatient Acceptance of Health CarePregnancy Complications, InfectiousPregnant PeopleVaccinationAdultChinaCross-Sectional StudiesFemaleHumansPregnancySurveys and QuestionnairesVaccination HesitancyInfluenza VaccinesbarriersfacilitatorsHealth Belief Model (HBM)pregnant womenSeasonal influenza vaccine

Identifiers

PMID40797352
PMCPMC12351702

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.