Evidence map›Paper›PMID 40797216›Full record

SynthesisBMC complementary medicine and therapies2025

Canine-assisted therapy in reducing stress and anxiety levels of university students: systematic review and meta-analysis of randomized controlled trials.

Shu Qing Sim, Zhiwei Liu, Zishuo Wu, Sian Wang, Claudia Nisa

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shu Qing Sim *Division of Social Sciences, Duke Kunshan University, Kunshan, China.
Zhiwei Liu *Division of Social Sciences, Duke Kunshan University, Kunshan, China.
Zishuo WuDuke University, Duke Global Health Institute, Durham, USA.
Sian WangLynch School of Education and Human Development, Boston College, Boston, USA.
Claudia NisaDivision of Social Sciences, Duke Kunshan University, Kunshan, China. cfn6@duke.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to the high prevalence of mental health issues among university students worldwide, canine-assisted therapy (CAT) has emerged as a potential intervention to reduce student stress and anxiety. This study systematically reviews and meta-analyzes the effects of CAT on reducing stress and anxiety levels among university students.

methodsFollowing the PRISMA 2020 guidelines, we conducted a systematic search across multiple databases (APA PsycINFO, PubMed, Duke Libraries, CNKI, Wanfang, and Google Scholar) for randomized controlled trials published in English and Chinese. Only studies incorporating professionally trained dogs and handlers were included. Two reviewers (SS and ZL) independently extracted data, and the risk of bias was assessed using the Cochrane Risk of Bias 2 tool. Effect sizes (Hedges' g) were pooled using a random-effects meta-analysis to account for the anticipated clinical and methodological heterogeneity. Subgroup analyses were conducted to explore moderators such as intervention duration, baseline stress levels, and control condition types. Publication bias was evaluated using funnel plots, Egger's test, and trim‑and‑fill analysis.

resultsOf 290 identified studies, 15 met the inclusion criteria and 14 were included in the meta-analysis. The meta-analysis yielded a statistically significant overall effect size of g = -0.67 (p <.001), indicating a moderate reduction in stress and anxiety among university students receiving CAT. Forest plots revealed effect sizes ranging from approximately - 1.34 to -0.13 across studies. Although substantial heterogeneity was observed, subgroup analyses showed that CAT was significantly more effective for students with high baseline stress and anxiety levels. Funnel-plot asymmetry suggested possible bias, but Egger's test was non‑significant. Trim‑and‑fill analysis imputed two missing studies, adjusting the pooled effect to g = -0.59, indicating the findings remain robust.

conclusionCAT demonstrates promise in alleviating stress and anxiety among university students. Despite methodological variations and potential publication bias, the findings suggest that CAT may offer a feasible and accessible approach to enhancing mental well-being within university environments. Further studies are necessary to examine factors influencing methodological diversity and refine the integration of CAT within university settings.

Indexed as

Animal Assisted TherapyAnxietyStress, PsychologicalStudentsAnimalsDogsHumansRandomized Controlled Trials as TopicUniversitiesAnxiety levelCanine-assisted therapyMeta-AnalysisRandomized controlled trialsStress levelSystematic reviewUniversity students

Identifiers

PMID40797216
PMCPMC12341270

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.