Evidence map›Paper›PMID 40797175›Full record

ArticleJournal of clinical ultrasound : JCU2026

Assessing the Utility of Targeted Neonatal Echocardiography for Congenital Heart Disease Detection: Retrospective Cohort Analysis.

Eyad Bitar, Aimann Surak, Rula Agarushi, Dawn Pepper, Matt Hicks, Abbas Hyderi, Lisa K Hornberger, Luke Eckersley, Kumar Kumaran

Abstract read
In one paragraph

Article in Journal of clinical ultrasound : JCU, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eyad BitarDepartment of Pediatrics, Division of Neonatal-Perinatal Care (NICU), University of Alberta, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0002-4422-8248
Aimann SurakDepartment of Pediatrics, Division of Neonatal-Perinatal Care (NICU), University of Alberta, Edmonton, Alberta, Canada.
Rula AgarushiDepartment of Pediatrics, Division of Neonatal-Perinatal Care (NICU), University of Alberta, Edmonton, Alberta, Canada.
Dawn PepperDepartment of Pediatrics, Division of Neonatal-Perinatal Care (NICU), University of Alberta, Edmonton, Alberta, Canada.
Matt HicksDepartment of Pediatrics, Division of Neonatal-Perinatal Care (NICU), University of Alberta, Edmonton, Alberta, Canada.
Abbas HyderiDepartment of Pediatrics, Division of Neonatal-Perinatal Care (NICU), University of Alberta, Edmonton, Alberta, Canada.
Lisa K HornbergerDepartment of Pediatrics, Division of Pediatrics Cardiology, University of Alberta, Edmonton, Alberta, Canada.
Luke EckersleyDepartment of Pediatrics, Division of Pediatrics Cardiology, University of Alberta, Edmonton, Alberta, Canada.
Kumar KumaranDepartment of Pediatrics, Division of Neonatal-Perinatal Care (NICU), University of Alberta, Edmonton, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTargeted neonatal echocardiography (TNE) is increasingly utilized by neonatologists to assess hemodynamics, particularly when cardiology-performed echocardiography (CPE) is unavailable. It is crucial that TNE screens and identifies structural abnormalities. This study evaluated the agreement between TNE and CPE in detecting significant congenital heart disease (CHD).

methodsThis retrospective, single-center cohort study included infants who underwent TNE between 2015 and 2019 and had at least one complete CPE before discharge. Infants with a known CHD diagnosis prior to TNE were excluded. Atrial septal defects (ASD) < 3 mm, peripheral pulmonary stenosis, and patent ductus arteriosus were excluded. Agreement between TNE and CPE was assessed using correlation coefficients and kappa statistics.

resultsA total of 339 infants with 954 TNE scans were included. TNE identified CHD in 41 infants, with all but one (a false positive bicuspid aortic valve) confirmed by CPE. TNE missed CHD in 29 infants (31 lesions), mostly minor, with only one case (pulmonary stenosis) requiring intervention. The overall agreement was 91.15%, with a kappa of 0.68 (p < 0.0001).

conclusionTNE demonstrated good agreement with CPE in detecting significant CHD in a low-risk neonatal population. Most missed lesions were minor, underscoring the importance of ongoing training and quality assurance.

Indexed as

EchocardiographyHeart Defects, CongenitalCohort StudiesFemaleHumansInfant, NewbornMaleReproducibility of ResultsRetrospective StudiesCHDcongenital heart diseaseneonatal intensive care unitNICUtargeted neonatal echocardiographyTNE

Identifiers

PMID40797175
PMCPMC12766864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.