Evidence map›Paper›PMID 40797093›Full record

ArticleScientific reports2025

Combined preoperative platelet-albumin ratio and cancer inflammation prognostic index predicts prognosis in colorectal cancer: a retrospective study.

Kuan Wang, Kejin Li, Ziyi Zhang, Xiangyue Zeng, Zhimin Wu, Boxiang Zhang, Yipeng Pan, Lucy Yue Lau, Zeliang Zhao, Yi Chen

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kuan WangDepartment of Gastrointestinal Surgery, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830011, China.
Kejin LiDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510000, Guangdong, China.
Ziyi ZhangDepartment of Gastrointestinal Surgery, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830011, China.
Xiangyue ZengDepartment of Gastrointestinal Surgery, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830011, China.
Zhimin WuDepartment of Otorhinolaryngology Head and Neck Surgery, The Maternal and Child Health Care Hospital of Guizhou Medical University, Guiyang, 550003, Guizhou, China.
Boxiang ZhangCancer Research Institute, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China.
Yipeng PanDepartment of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310020, Zhejiang, China.
Lucy Yue LauDepartment of Public health, Harvard Medical School, Boston, MA, 02115, USA.
Zeliang ZhaoDepartment of Gastrointestinal Surgery, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830011, China. zlzhao71@163.com.
Yi ChenCancer Research Institute, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China. chenyicsu@outlook.com.

Funding

the Natural Science Foundation of Xinjiang Uygur Autonomous Region No. 2022D01C297
6 · The paper itself

Abstract

Colorectal cancer (CRC) has one of the highest incidence and mortality rates of any cancer worldwide, and the recurrence and metastasis rates after surgery remain high. The search for simple and reliable prognostic markers is essential to improve patient prognosis. In this study, we investigated the predictive value of two easy-to-measure preoperative markers, platelet-to-albumin ratio (PAR) and cancer inflammation prognostic index (CIPI), in postoperative survival of patients with CRC. We retrospectively analyzed the clinical data of a total of 434 CRC patients from two hospitals. Data from one of the institutions were used as a training cohort. The predictive ability of both markers was assessed using subject work characteristics (ROC) curves, with optimal cutoff values of 11.69 and 6.85 for CIPI and PAR, respectively, and high CIPI and PAR were independently associated with poorer overall survival. We developed nomogram of overall survival (OS), performed internal and external validation, and showed superior prognostic accuracy of the nomogram models. Our results suggest that combined CIPI and PAR can be used as a valid and accessible prognostic tool that is expected to help develop personalized treatment strategies for CRC patients.

Indexed as

Blood PlateletsColorectal NeoplasmsInflammationSerum AlbuminAdultAgedAged, 80 and overBiomarkers, TumorFemaleHumansMaleMiddle AgedNomogramsPlatelet CountPreoperative PeriodPrognosisBiomarkers, TumorSerum AlbuminColorectal cancerNomogramOverall survivalPlatelet-albumin ratioPrognosis

Identifiers

PMID40797093
PMCPMC12343761

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.