Evidence map›Paper›PMID 40797003›Full record

ReviewNeurology and therapy2025

Advances in Ischemic Stroke Treatment: Current and Future Therapies.

Benjamin W Y Lo, Hitoshi Fukuda

Abstract readReview
In one paragraph

Review in Neurology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. [A review of noninvasive brain-computer interfaces combined with transcranial electrical stimulation for neural rehabilitation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Review
  5. Observational
  6. Predictive Value of D-Dimer to Fibrinogen Ratio for Unfavorable Outcomes in Acute Ischemic Stroke Patients Undergoing Intravenous Thrombolysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Benjamin W Y LoDivision of Neurosurgery, Queen Mary Hospital, Hong Kong Hospital Authority, Hong Kong, China. lo_benjamin@hotmail.com.
Hitoshi FukudaDepartment of Neurosurgery, Kochi University Hospital, Kochi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review summarizes current concepts in our understanding of stroke anatomy, pathophysiology of cerebral hypoperfusion, and collateral circulation. It also provides an evidence-based update in stroke trials and treatments assessed using PRISMA guidelines. Intravenous thrombolysis, endovascular thrombectomy for anterior circulation strokes, blood pressure control after endovascular thrombectomy, and medical management principles are discussed. Endovascular thrombectomy and medical therapy improves functional independence at 90 days in anterior circulation strokes even in late windows up to 24 h post symptom onset regardless of infarct core size. Intensive systolic blood pressure control acutely post thrombectomy is associated with harm and worse outcomes. This review also provides an evidence-based update on neurorehabilitation strategies with emerging interventions such as brain-computer interface and robotics having the potential to maximize neuroplasticity for potential improvement and recovery post stroke.

Indexed as

Brain–body interactionsCollateral circulationEndovascular thrombectomyEvidence-based updateStroke neurorehabilitationStroke syndromesStroke trialsThrombolytic therapy

Identifiers

PMID40797003
PMCPMC12450147

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.