Evidence map›Paper›PMID 40797000›Full record

SynthesisDigestive diseases and sciences2026

Efficacy of Whole-Food Based Anti-inflammatory Dietary Interventions in the Management of Ulcerative Colitis: A Systematic Review and Meta-Analysis.

Manayiel Rehmat, Umair Ul Haq, Muhammad Nabeel Saddique, Laiba Mehmood, Noor Fatima, Muhammad Younas, Muhammad Usman Iqbal, Muneeb Ur Rahman, Muhammad Anas Khan, Zeeshan Ul Haq

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manayiel RehmatKing Edward Medical University, Lahore, 54000, Pakistan.ORCID http://orcid.org/0009-0003-7838-0146
Umair Ul HaqBannu Medical College, Bannu, Pakistan.ORCID http://orcid.org/0009-0004-7489-5721
Muhammad Nabeel SaddiqueKing Edward Medical University, KEMU Boys Hostel, Link McLeod Road, Lahore, 54000, Pakistan. nabeelsaddique@kemu.edu.pk.
Laiba MehmoodKing Edward Medical University, KEMU Boys Hostel, Link McLeod Road, Lahore, 54000, Pakistan.ORCID http://orcid.org/0009-0007-9777-7973
Noor FatimaGomal Medical College, Dera Ismail Khan, Pakistan.ORCID http://orcid.org/0009-0003-0987-0272
Muhammad YounasGomal Medical College, Dera Ismail Khan, Pakistan.
Muhammad Usman IqbalKing Edward Medical University, KEMU Boys Hostel, Link McLeod Road, Lahore, 54000, Pakistan.ORCID http://orcid.org/0009-0001-3552-546X
Muneeb Ur RahmanBannu Medical College, Bannu, Pakistan.
Muhammad Anas KhanBannu Medical College, Bannu, Pakistan.
Zeeshan Ul HaqKhalifa Gul Nawaz Teaching Hospital, Bannu, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUlcerative Colitis (UC) is a chronic inflammatory colon condition with multifactorial causation. Recent interest has grown around the role of diet in managing symptoms and disease progression. Due to the absence of definitive evidence, no consistent dietary guidelines exist for UC management.

aimsThis research investigates the impact of anti-inflammatory diets on disease activity and inflammation in patients with UC.

methodsPubMed, Cochrane, Embase and ClinicalTrials.gov were systematically searched from inception until April 2025. Dichotomous outcomes were pooled as risk ratio (RR) and continuous outcomes as mean differences (MD) with 95% confidence intervals (CI), using random-effects models. Heterogeneity was assessed using I

resultsSix RCTs involving 359 patients aged 12-75 years, having mild-to-moderate active UC, quiescent UC or UC in clinical remission, were included. Anti-inflammatory diets did not significantly affect the clinical remission (RR = 1.59, 95% CI [0.77 to 3.28], P = 0.21, I

conclusionAnti-inflammatory diet complements conventional therapy in UC by promoting clinical response in active disease and reducing intestinal inflammation during remission.

Indexed as

Colitis, UlcerativeHumansRandomized Controlled Trials as TopicRemission InductionTreatment OutcomeAnti-inflammatory dietMediterranean dietMeta-analysisUlcerative colitis

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.