Efficacy and safety of flexible and navigable suction access sheaths versus traditional access sheath in flexible ureteroscopic lithotripsy: a systematic review and meta-analysis.

purposeThis study aims to evaluate the efficacy and safety of flexible and navigable suction access sheath (FANS) and traditional ureteral access sheath (T-UAS) combined with flexible ureteroscope in treating upper urinary tract calculi.

methodA systematic review and meta-analysis were conducted by searching databases such as PubMed, EMBASE, Medline, Web of Science, and the Cochrane Library. Results were filtered using pre-defined inclusion and exclusion criteria as described, and meta-analysis was performed using Review Manager 5.3 software.

resultsA total of 10 literatures were included, involving 2105 patients. The meta-analysis results demonstrated that compared with the T-UAS group, the FANS group had a higher stone free rate (SFR) (the immediate postoperative SFR was 79.1% vs 56.5%, OR = 2.87, 95% CI: 2.24-3.66, P < 0.05; the SFR at 1 month after surgery was 92.0% vs 79.9%, OR = 2.98, 95% CI: 2.27-3.91, P < 0.05); a lower total complication rate (7.2% vs 19.0%, OR = 0.37, 95% CI: 0.27-0.49, P < 0.05); less fever (3.3% vs 10.4%, OR = 0.31, 95% CI: 0.21-0.46, P < 0.05); a lower incidence of steinstrasse (0.0% vs 2.6%, OR = 0.16, 95% CI: 0.03-0.90, P < 0.05); there was no significant difference in the incidence of hematuria (3.9% vs 7.0%, OR = 0.56, 95% CI: 0.22-1.42, P > 0.05), ureteral mucosal injury (2.0% vs 3.8%, OR = 0.64, 95% CI: 0.26-1.57, P > 0.05) and operation time (MD =- 1.69, 95% CI:- 2.62-5.99, P > 0.05).

conclusionCompared with the T-UAS combined with flexible ureteroscopy, the FANS has a higher SFR. However, the two have comparable incidences of some short-term complications, and there is a lack of comparison of long-term postoperative complications. Although the total complication rate of the bendable sheath is currently lower, further exploration is still needed.