Evidence map›Paper›PMID 40796934›Full record

ArticleCommunications biology2025

Detection of EEG dynamic complex patterns in disorders of consciousness.

Gabriel A Della Bella, Di Zang, Peng Gui, Diego M Mateos, Jacobo D Sitt, Tristan A Bekinschtein, Dragana Manasova, Benjamine Sarton, Fabrice Ferre, Stein Silva and 5 more

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gabriel A Della Bella *Cognitive Science Group. Instituto de Investigaciones Psicológicas (IIPsi,CONICET-UNC), Facultad de Psicología, Universidad Nacional de Córdoba, Córdoba, Argentina. dellabellagabriel@gmail.com.ORCID http://orcid.org/0000-0001-8433-0725
Di Zang *Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Peng Gui *Institute of Neuroscience, Key Laboratory of Brain Cognition and Brain-Inspired Intelligence Technology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. pgui@ion.ac.cn.ORCID http://orcid.org/0000-0002-9848-7050
Diego M MateosConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Jacobo D SittSorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France.
Tristan A BekinschteinDepartment of Psychology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5501-8628
Dragana ManasovaSorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France.
Benjamine SartonRéanimation URM CHU Purpan, Cedex, Toulouse, France.
Fabrice FerreRéanimation URM CHU Purpan, Cedex, Toulouse, France.
Stein SilvaRéanimation URM CHU Purpan, Cedex, Toulouse, France.
Pedro W LambertiFacultad de Matemática, Astronomía, Física y Computación (FaMAF), Universidad Nacional de Córdoba, Córdoba, Argentina.
Xuehai WuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-4216-6685
Ying MaoDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-8055-115X
Liping WangInstitute of Neuroscience, Key Laboratory of Brain Cognition and Brain-Inspired Intelligence Technology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.
Pablo BarttfeldCognitive Science Group. Instituto de Investigaciones Psicológicas (IIPsi,CONICET-UNC), Facultad de Psicología, Universidad Nacional de Córdoba, Córdoba, Argentina.ORCID http://orcid.org/0000-0001-8530-6938

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosing Disorders of Consciousness (DoC) remains a critical challenge in cognitive neuroscience. In this study we introduce Electroencephalography (EEG)-based brain states as a real-time, bedside tool for assessing dynamic brain connectivity in DoC patients. We analyze EEG data from 237 acute and chronic DoC patients across three centers, identifying five recurrent functional connectivity patterns. The probability of these patterns correlated strongly with consciousness levels, with high-entropy patterns exclusive to healthy controls and low-entropy patterns prevalent in severe DoC, predicting individual recovery outcomes. Real-time testing validated reliable bedside detection of these patterns. Our findings demonstrate EEG's potential for monitoring dynamic brain connectivity, offering insights into the neural basis of consciousness and advancing diagnostic strategies for DoC.

Indexed as

BrainConsciousness DisordersElectroencephalographyAdultAgedConsciousnessFemaleHumansMaleMiddle Aged

Identifiers

PMID40796934
PMCPMC12344011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.