Evidence map›Paper›PMID 40796847›Full record

SynthesisBMC women's health2025

Is hypertension negatively associated with memory performance in women during climacteric? A systematic review.

Arthur Polveiro da Silva, Laura Scatena Fávero, Adriano Bruno Corrêa, Mateus do Carmo Bardella, Luís Felipe Pengo Almeida Leite, Leonardo Santos Lopes da Silva, Márcio Fernando Tasinafo Júnior, Leonardo da Silva Gonçalves, Camila de Moraes

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arthur Polveiro da SilvaSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil. apolveiro@usp.br.
Laura Scatena FáveroSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.
Adriano Bruno CorrêaSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.
Mateus do Carmo BardellaSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.
Luís Felipe Pengo Almeida LeiteSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.
Leonardo Santos Lopes da SilvaSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.
Márcio Fernando Tasinafo JúniorSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.
Leonardo da Silva GonçalvesSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.
Camila de MoraesSchool of Physical Education and Sports of Ribeirao Preto, University of São Paulo, Av Bandeirantes, 3900, Ribeirão Preto, SP, 14040-900, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

backgroundThe negative association between hypertension and memory performance has been a subject of broad debate in recent decades. Considering the neuroendocrine changes that occur during climacteric, this systematic review aimed to investigate whether hypertension is negatively associated with memory performance in women during climacteric.

methodsA comprehensive search was conducted in the MEDLINE, EMBASE, Web of Science, Scopus, and BVS electronic databases according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Studies involving hypertensive, middle-aged women in the climacteric phase were included. The risk of bias and methodological quality was assessed using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies (NHLBI, NIH).

resultsOut of 16 studies selected for the full-text reading phase, 5 were included in the systematic review. The included studies were predominantly longitudinal. Heterogeneity was observed in the sample size, and the tools for assessing memory, reproductive stage, and hypertension diagnosis. Two longitudinal studies reported a negative association between hypertension and memory performance, while one found no significant association. The cross-sectional studies reported that hypertensive participants demonstrated poorer memory performance compared to normotensive participants.

conclusionsBased on the included studies, the results suggests that hypertension is negatively associated with memory performance in climacteric women. However, due to the small number of studies and the fact that most were conducted in developed countries, these results should be interpreted with caution (PROSPERO registration number: CRD42023391668).

Indexed as

ClimactericHypertensionMemoryMemory DisordersMenopauseCross-Sectional StudiesFemaleHumansMiddle AgedBlood pressureClimactericCognitive functionMenopause

Identifiers

PMID40796847
PMCPMC12344873

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.