ArticleBMC psychiatry2025
Fear of progression profiles and their association with quality of life and depression in ischemic stroke survivors: a latent profile analysis.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- Fear of progression and association factors in stroke patients: a latent profile analysis.Frontiers in psychology · 2026Article
- Demoralization profiles and their association with active aging in Chinese older adults with disabilities: a latent profile analysis.Frontiers in public health · 2025Article
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6 authors.
Funding
Abstract
backgroundFear of progression (FoP) has been well-documented in patients with cancer and chronic disease. However, there is little information in stroke patients. The purpose of this study was to explore the profiles and associated factors of FoP among ischemic stroke survivors, and to examine the association of FoP profiles with quality of life (QoL) and depression.
methodsA cross-sectional study was conducted from July 2023 to June 2024. Two hundred ischemic stroke survivors were recruited. Data collection included a self-designed sociodemographic and clinical information questionnaire, the Fear of Progression Questionnaire-Short Form, the Stroke Specific Quality of Life Scale, and the Self-Rating Depression Scale. Latent profile analysis (LPA), univariate analysis, multinomial logistic regression analysis, and multiple hierarchical regression analysis were adopted in this study.
resultsLPA identified three subgroups of FoP: Group 1-the low FoP (23%), Group 2-the moderate FoP with family-related concerns (45%), and Group 3-the high FoP with work-related concerns (32%). Older age (OR = 0.245, p = 0.003) and lower functional independence (Barthel index, BI) (OR = 0.976, p = 0.034) were associated with Group 2, while younger age (OR = 8.771, p = 0.018) and lower monthly family income (OR = 9.960, p = 0.004) were associated with Group 3. FoP profiles explained 3.0% variance in QoL and 3.3% variance in depression (p < 0.05). Group 2 and 3 showed significantly lower QoL than Group 1 (p < 0.05), while Group 2 and Group 3 had higher depression than Group 1 (p < 0.05).
conclusionThree heterogeneous subgroups of FoP were identified in ischemic stroke survivors. Age, household monthly income, and functional independence were associated with different latent profiles of FoP. Healthcare providers should categorize patients with FoP into subgroups and provide targeted interventions based on each profile's characteristics and associated factors. This could contribute to promoting their QoL and lowering their depression.
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